TY - JOUR
T1 - Epigenetic silencing of the 3p22 tumor suppressor DLEC1 by promoter CpG methylation in non-Hodgkin and Hodgkin lymphomas
AU - Wang, Zhaohui
AU - Li, Lili
AU - Su, Xianwei
AU - Gao, Zifen
AU - Srivastava, Gopesh
AU - Murray, Paul G
AU - Ambinder, Richard
AU - Tao, Qian
PY - 2012
Y1 - 2012
N2 - Inactivation of tumor suppressor genes (TSGs) by promoter CpG methylation frequently occurs in tumorigenesis, even in the early stages, contributing to the initiation and progression of human cancers. Deleted in lung and esophageal cancer 1 (DLEC1), located at the 3p22-21.3 TSG cluster, has been identified frequently silenced by promoter CpG methylation in multiple carcinomas, however, no study has been performed for lymphomas yet.
AB - Inactivation of tumor suppressor genes (TSGs) by promoter CpG methylation frequently occurs in tumorigenesis, even in the early stages, contributing to the initiation and progression of human cancers. Deleted in lung and esophageal cancer 1 (DLEC1), located at the 3p22-21.3 TSG cluster, has been identified frequently silenced by promoter CpG methylation in multiple carcinomas, however, no study has been performed for lymphomas yet.
U2 - 10.1186/1479-5876-10-209
DO - 10.1186/1479-5876-10-209
M3 - Article
C2 - 23050586
SN - 1479-5876
VL - 10
SP - 209
JO - Journal of translational medicine
JF - Journal of translational medicine
ER -
