Improving citizens’ quality of life is a stated priority of many governments in both the global north and south. However, efforts to achieve this often focus on socio-economic measures, with limited attention to the contributions of environmental variables such as green spaces. This paper sought to bridge this knowledge gap by tracing the linkages between green spaces and quality of life, and how these connections can inform policy development in order to assist governments to achieve positive outcomes for quality of life. The paper took a theoretical approach by utilising the systematic review method. In all, 452 publications were included in this review, and rigorous content analysis was employed to retrieve relevant data. Green spaces were found to provide various social, economic, and environmental benefits, which in turn improve physical, psychological, emotional, social, and material wellbeing of individuals and thus enhance quality of life. It is therefore strongly recommended that conservation of green spaces should be integrated into national health, environmental and socio-economic policies in order to promote effective utilisation of green spaces to enhance citizens’ overall quality of life.