Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390

AC Murphy; D Fukuda; Z Song; Joanne Hothersall; RJ Cox; CL Willis; Christopher Thomas; TJ Simpson

doi:10.1002/anie.201007029

Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390

AC Murphy, D Fukuda, Z Song, Joanne Hothersall, RJ Cox, CL Willis, Christopher Thomas, TJ Simpson

Biosciences

Research output: Contribution to journal › Article

32 Citations (Scopus)

Original language	English
Pages (from-to)	3271-3274
Number of pages	4
Journal	Angewandte Chemie (International Edition)
Volume	50
Issue number	14
DOIs	https://doi.org/10.1002/anie.201007029
Publication status	Published - 1 Jan 2011

Keywords

antibiotics
mupirocin
thiomarinol
methicillin resistance
biosynthesis

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10.1002/anie.201007029

Biosynthesis of polyketide antibiotic mupirocin by Pseudomonas fluorescens
Thomas, C. (Principal Investigator)
Biotechnology & Biological Sciences Research Council
1/06/07 → 30/01/11
Project: Research Councils

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title = "Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390",

keywords = "antibiotics, mupirocin, thiomarinol, methicillin resistance, biosynthesis",

author = "AC Murphy and D Fukuda and Z Song and Joanne Hothersall and RJ Cox and CL Willis and Christopher Thomas and TJ Simpson",

year = "2011",

month = jan,

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doi = "10.1002/anie.201007029",

language = "English",

volume = "50",

pages = "3271--3274",

journal = "Angewandte Chemie (International Edition) ",

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publisher = "Wiley-VCH Verlag",

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T1 - Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390

AU - Murphy, AC

AU - Fukuda, D

AU - Song, Z

AU - Hothersall, Joanne

AU - Cox, RJ

AU - Willis, CL

AU - Thomas, Christopher

AU - Simpson, TJ

PY - 2011/1/1

Y1 - 2011/1/1

KW - antibiotics

KW - mupirocin

KW - thiomarinol

KW - methicillin resistance

KW - biosynthesis

U2 - 10.1002/anie.201007029

DO - 10.1002/anie.201007029

M3 - Article

C2 - 21381163

SN - 1521-3773

VL - 50

SP - 3271

EP - 3274

JO - Angewandte Chemie (International Edition)

JF - Angewandte Chemie (International Edition)

IS - 14

ER -

Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390

Keywords

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Projects

Biosynthesis of polyketide antibiotic mupirocin by Pseudomonas fluorescens

Cite this