Endogenous cardiotonic steroids and cardiovascular disease, where to next?

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• Finished

  Investigating regulatory pathways for intracellular sodium in the atria

  Pavlovic, D. & Thomas, S.

  British Heart Foundation

  1/10/19 → 30/04/23

  Project: Research

  • Atrial Fibrillation 100%
  • Cardiac Myocytes 83%
  • Voltage-Sensitive Dye Imaging 74%
  • Fibroblasts 66%
  • Cardiac Glycosides 61%

• Scarred by kidney disease: FGF23 as a key mediator of cardiac fibrosis in patients with chronic kidney disease

  Weston, C., Pavlovic, D., McGettrick, H. & Gough, R.

  British Heart Foundation

  1/08/19 → 28/02/23

  Project: Research

  • Atrial Fibrillation 100%
  • Cardiac Myocytes 83%
  • Voltage-Sensitive Dye Imaging 74%
  • Cardiac Glycosides 61%
  • Sodium-Potassium-Exchanging ATPase 60%

• Cardiotonic steroids in patients with atrial fibrillation and heart failure: Quantification, functional effects and personalisation of digoxin therapy

  Arlt, W., Pavlovic, D., Taylor, A., Kotecha, D. & Kirchhof, P.

  British Heart Foundation

  1/06/18 → 30/05/21

  Project: Research

  • Atrial Fibrillation 100%
  • Heart Failure 54%
  • Cardiac Myocytes 46%
  • Voltage-Sensitive Dye Imaging 41%
  • Cardiac Electrophysiology 40%

• Examining the role of endogenous cardiotonic steriods in cardiovascular disease development.

  Pavlovic, D.

  THE WELLCOME TRUST

  1/04/16 → 31/03/18

  Project: Research

  • Cardiac Electrophysiology 100%
  • Action Potential 89%
  • Cardiac Glycosides 82%
  • Calcium 82%
  • Sodium-Potassium-Exchanging ATPase 82%