TY - JOUR
T1 - Emergent complexity from simple anisotropic building blocks
T2 - Shells, tubes, and spirals
AU - Fejer, S.N.
AU - Chakrabarti, D.
AU - Wales, D.J.
PY - 2010/1/26
Y1 - 2010/1/26
N2 - We describe a remarkably simple, generic, coarse-grained model involving anisotropic interactions, and characterize the global minima for clusters as a function of various parameters. Appropriate choices for the anisotropic interactions can reproduce a wide variety of complex morphologies as global minima, including spheroidal shells, tubular, helical and even head-tail morphologies, elucidating the physical principles that drive the assembly of these mesoscopic structures. Our model captures several experimental observations, such as the existence of competing morphologies, capsid polymorphism, and the effect of scaffolding proteins on capsid assembly.
AB - We describe a remarkably simple, generic, coarse-grained model involving anisotropic interactions, and characterize the global minima for clusters as a function of various parameters. Appropriate choices for the anisotropic interactions can reproduce a wide variety of complex morphologies as global minima, including spheroidal shells, tubular, helical and even head-tail morphologies, elucidating the physical principles that drive the assembly of these mesoscopic structures. Our model captures several experimental observations, such as the existence of competing morphologies, capsid polymorphism, and the effect of scaffolding proteins on capsid assembly.
UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-75749138541&partnerID=8YFLogxK
U2 - 10.1021/nn9013565
DO - 10.1021/nn9013565
M3 - Article
AN - SCOPUS:75749138541
SN - 1936-0851
VL - 4
SP - 219
EP - 228
JO - ACS Nano
JF - ACS Nano
IS - 1
ER -