Elucidation of the structure and intermolecular interactions of a reversible cyclic-peptide inhibitor of the proteasome by NMR spectroscopy and molecular modeling

Benjamin Stauch, Bernd Simon, Teodora Basile, Gisbert Schneider, Nisar P Malek, Markus Kalesse, Teresa Carlomagno

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)3934-8
Number of pages5
JournalAngewandte Chemie (International Edition)
Volume49
Issue number23
DOIs
Publication statusPublished - 25 May 2010

Keywords

  • Antineoplastic Agents/chemistry
  • Binding Sites
  • Enzyme Inhibitors/chemistry
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Peptides, Cyclic/chemistry
  • Proteasome Endopeptidase Complex/chemistry
  • Protein Binding
  • Structure-Activity Relationship

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