Electrographic high-frequency activity and epilepsy.

Premysl Jiruska; Andrew Powell; WC Chang; John Jefferys

doi:10.1016/j.eplepsyres.2009.11.008

Electrographic high-frequency activity and epilepsy.

Premysl Jiruska, Andrew Powell, WC Chang, John Jefferys

Birmingham Medical School

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Abstract

High-frequency electrographic activity (HFA) has a frequency of 80-600Hz. It can be observed interictally in epileptic foci and also at the onset of epileptic seizures. There are several hypotheses about how HFA is generated, and it has been suggested that the underlying mechanisms may play an important role in epileptogenesis and ictogenesis. The high specificity of HFA for epileptic foci is now used during presurgical evaluation to help localize epileptic focus. In this article we review the current state of knowledge regarding this phenomenon and challenges for the future studies focusing on HFA.

Original language	English
Journal	Epilepsy Research
Early online date	21 Dec 2009
DOIs	https://doi.org/10.1016/j.eplepsyres.2009.11.008
Publication status	Published - 21 Dec 2009

Keywords

Ripples
High-frequency activity
Epilepsy
Fast ripples
Epileptogenesis
Ictogenesis

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10.1016/j.eplepsyres.2009.11.008

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title = "Electrographic high-frequency activity and epilepsy.",

abstract = "High-frequency electrographic activity (HFA) has a frequency of 80-600Hz. It can be observed interictally in epileptic foci and also at the onset of epileptic seizures. There are several hypotheses about how HFA is generated, and it has been suggested that the underlying mechanisms may play an important role in epileptogenesis and ictogenesis. The high specificity of HFA for epileptic foci is now used during presurgical evaluation to help localize epileptic focus. In this article we review the current state of knowledge regarding this phenomenon and challenges for the future studies focusing on HFA.",

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AU - Chang, WC

AU - Jefferys, John

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AB - High-frequency electrographic activity (HFA) has a frequency of 80-600Hz. It can be observed interictally in epileptic foci and also at the onset of epileptic seizures. There are several hypotheses about how HFA is generated, and it has been suggested that the underlying mechanisms may play an important role in epileptogenesis and ictogenesis. The high specificity of HFA for epileptic foci is now used during presurgical evaluation to help localize epileptic focus. In this article we review the current state of knowledge regarding this phenomenon and challenges for the future studies focusing on HFA.

KW - Ripples

KW - High-frequency activity

KW - Epilepsy

KW - Fast ripples

KW - Epileptogenesis

KW - Ictogenesis

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JO - Epilepsy Research

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ER -

Electrographic high-frequency activity and epilepsy.

Abstract

Keywords

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