Electrical and mechanical components of dyssynchrony in heart failure patients with normal QRS duration and left bundle-branch block: impact of left and biventricular pacing

MS Turner; RA Bleasdale; D Vinereanu; CE Mumford; V Paul; AG Fraser; Michael Frenneaux

doi:10.1161/01.CIR.0000131184.40893.40

Electrical and mechanical components of dyssynchrony in heart failure patients with normal QRS duration and left bundle-branch block: impact of left and biventricular pacing

MS Turner, RA Bleasdale, D Vinereanu, CE Mumford, V Paul, AG Fraser, Michael Frenneaux

Birmingham Medical School

Research output: Contribution to journal › Article

138 Citations (Scopus)

Abstract

BACKGROUND: Resynchronization pacing is an effective symptomatic treatment for heart failure patients with prolongation of the QRS duration (QRSd). Dyssynchronous contraction of the left ventricle is also observed with normal QRSd. We set out to determine how electrical activation of the left ventricular (LV) free wall differed between patients with left bundle-branch block (LBBB) and normal QRSd and if synchrony improved during pacing in patients with normal QRSd. METHODS AND RESULTS: Twenty-two patients were implanted with resynchronization pacemakers, 13 with LBBB (mean QRS, 171 ms) and 9 with normal QRSd

Original language	English
Pages (from-to)	2544-2549
Number of pages	6
Journal	Circulation
Volume	109
DOIs	https://doi.org/10.1161/01.CIR.0000131184.40893.40
Publication status	Published - 1 Jan 2004

Access to Document

10.1161/01.CIR.0000131184.40893.40

Cite this

@article{ae9e67a8973b42b2ade52eca4d16e376,

title = "Electrical and mechanical components of dyssynchrony in heart failure patients with normal QRS duration and left bundle-branch block: impact of left and biventricular pacing",

abstract = "BACKGROUND: Resynchronization pacing is an effective symptomatic treatment for heart failure patients with prolongation of the QRS duration (QRSd). Dyssynchronous contraction of the left ventricle is also observed with normal QRSd. We set out to determine how electrical activation of the left ventricular (LV) free wall differed between patients with left bundle-branch block (LBBB) and normal QRSd and if synchrony improved during pacing in patients with normal QRSd. METHODS AND RESULTS: Twenty-two patients were implanted with resynchronization pacemakers, 13 with LBBB (mean QRS, 171 ms) and 9 with normal QRSd ",

author = "MS Turner and RA Bleasdale and D Vinereanu and CE Mumford and V Paul and AG Fraser and Michael Frenneaux",

year = "2004",

month = jan,

day = "1",

doi = "10.1161/01.CIR.0000131184.40893.40",

language = "English",

volume = "109",

pages = "2544--2549",

journal = "Circulation",

issn = "1524-4539",

publisher = "American Heart Association",

}

TY - JOUR

T1 - Electrical and mechanical components of dyssynchrony in heart failure patients with normal QRS duration and left bundle-branch block: impact of left and biventricular pacing

AU - Turner, MS

AU - Bleasdale, RA

AU - Vinereanu, D

AU - Mumford, CE

AU - Paul, V

AU - Fraser, AG

AU - Frenneaux, Michael

PY - 2004/1/1

Y1 - 2004/1/1

N2 - BACKGROUND: Resynchronization pacing is an effective symptomatic treatment for heart failure patients with prolongation of the QRS duration (QRSd). Dyssynchronous contraction of the left ventricle is also observed with normal QRSd. We set out to determine how electrical activation of the left ventricular (LV) free wall differed between patients with left bundle-branch block (LBBB) and normal QRSd and if synchrony improved during pacing in patients with normal QRSd. METHODS AND RESULTS: Twenty-two patients were implanted with resynchronization pacemakers, 13 with LBBB (mean QRS, 171 ms) and 9 with normal QRSd

AB - BACKGROUND: Resynchronization pacing is an effective symptomatic treatment for heart failure patients with prolongation of the QRS duration (QRSd). Dyssynchronous contraction of the left ventricle is also observed with normal QRSd. We set out to determine how electrical activation of the left ventricular (LV) free wall differed between patients with left bundle-branch block (LBBB) and normal QRSd and if synchrony improved during pacing in patients with normal QRSd. METHODS AND RESULTS: Twenty-two patients were implanted with resynchronization pacemakers, 13 with LBBB (mean QRS, 171 ms) and 9 with normal QRSd

UR - http://www.scopus.com/inward/record.url?scp=2642539260&partnerID=8YFLogxK

U2 - 10.1161/01.CIR.0000131184.40893.40

DO - 10.1161/01.CIR.0000131184.40893.40

M3 - Article

C2 - 15148267

SN - 1524-4539

VL - 109

SP - 2544

EP - 2549

JO - Circulation

JF - Circulation

ER -

Electrical and mechanical components of dyssynchrony in heart failure patients with normal QRS duration and left bundle-branch block: impact of left and biventricular pacing

Abstract

Access to Document

Fingerprint

Cite this