Efficacy of water preloading before main meals as a strategy for weight loss in primary care patients with obesity:: RCT

Helen Parretti; Paul Aveyard; Andrew Blannin; Susan Clifford; Sarah Coleman; Andrea Roalfe; Amanda Daley

doi:10.1002/oby.21167

Efficacy of water preloading before main meals as a strategy for weight loss in primary care patients with obesity: RCT

Helen Parretti, Paul Aveyard, Andrew Blannin, Susan Clifford, Sarah Coleman, Andrea Roalfe, Amanda Daley

Sport, Exercise and Rehabilitation Sciences

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

1008 Downloads (Pure)

Abstract

Objective: To investigate the efficacy of water preloading before meals as a weight loss strategy for adults with obesity.

Methods: Two group randomized controlled trial conducted in Birmingham, England. 84 adults with obesity were recruited from general practices. All participants were given a face to face weight management consultation at baseline (30 minutes) and a follow-up telephone consultation at two weeks (10 minutes). At baseline participants were randomized to either drinking 500mls of water 30 minutes before their main meals or an attention control group where participants were asked to imagine their stomach was full before meals. The primary outcome was weight change at 12 weeks follow up. Several measures of adherence were also used, including 24hr total urine collections.

Results: 41 participants were randomized to the intervention group and 43 to the comparator group. The water preloading group lost -1.3kg (95% CI -2.4 to -0.1, p=0.028) more than comparators at follow up. Adjusting for ethnicity, deprivation, age and gender resulted in the intervention group losing -1.2kg (95% CI -2.4 to 0.07, p=0.063) more than the comparator.

Conclusion: There is preliminary evidence that water preloading before main meals leads to a moderate weight loss at follow up. ISRCTN33238158

Original language	English
Pages (from-to)	1785-1791
Journal	Obesity
Volume	23
Issue number	9
Early online date	3 Aug 2015
DOIs	https://doi.org/10.1002/oby.21167
Publication status	Published - 1 Sept 2015

Keywords

weight loss
clinical trials
primary care
obesity

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/oby.21167Licence: None: All rights reserved

parretti_waterpreloadingRCT
This is the peer reviewed version of the following article: Parretti, H. M., Aveyard, P., Blannin, A., Clifford, S. J., Coleman, S. J., Roalfe, A. and Daley, A. J. (2015), Efficacy of water preloading before main meals as a strategy for weight loss in primary care patients with obesity: RCT. Obesity. This has been published in final form at doi: 10.1002/oby.21167 This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. Eligibility for repository: checked 10/08/2015
Accepted author manuscript, 155 KBLicence: Other (please specify with Rights Statement)
Parretti_waterpreloadingRCT_figure1
This is the peer reviewed version of the following article: Parretti, H. M., Aveyard, P., Blannin, A., Clifford, S. J., Coleman, S. J., Roalfe, A. and Daley, A. J. (2015), Efficacy of water preloading before main meals as a strategy for weight loss in primary care patients with obesity: RCT. Obesity. This has been published in final form at doi: 10.1002/oby.21167 This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. Eligibility for repository: checked 10/08/2015
Accepted author manuscript, 122 KBLicence: Other (please specify with Rights Statement)

http://onlinelibrary.wiley.com/doi/10.1002/oby.21167/abstract;jsessionid=21E8F43D141FDADD10141A243B8D590E.f03t04Licence: None: All rights reserved

Cite this

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title = "Efficacy of water preloading before main meals as a strategy for weight loss in primary care patients with obesity:: RCT",

abstract = "Objective: To investigate the efficacy of water preloading before meals as a weight loss strategy for adults with obesity. Methods: Two group randomized controlled trial conducted in Birmingham, England. 84 adults with obesity were recruited from general practices. All participants were given a face to face weight management consultation at baseline (30 minutes) and a follow-up telephone consultation at two weeks (10 minutes). At baseline participants were randomized to either drinking 500mls of water 30 minutes before their main meals or an attention control group where participants were asked to imagine their stomach was full before meals. The primary outcome was weight change at 12 weeks follow up. Several measures of adherence were also used, including 24hr total urine collections. Results: 41 participants were randomized to the intervention group and 43 to the comparator group. The water preloading group lost -1.3kg (95% CI -2.4 to -0.1, p=0.028) more than comparators at follow up. Adjusting for ethnicity, deprivation, age and gender resulted in the intervention group losing -1.2kg (95% CI -2.4 to 0.07, p=0.063) more than the comparator. Conclusion: There is preliminary evidence that water preloading before main meals leads to a moderate weight loss at follow up. ISRCTN33238158",

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N2 - Objective: To investigate the efficacy of water preloading before meals as a weight loss strategy for adults with obesity. Methods: Two group randomized controlled trial conducted in Birmingham, England. 84 adults with obesity were recruited from general practices. All participants were given a face to face weight management consultation at baseline (30 minutes) and a follow-up telephone consultation at two weeks (10 minutes). At baseline participants were randomized to either drinking 500mls of water 30 minutes before their main meals or an attention control group where participants were asked to imagine their stomach was full before meals. The primary outcome was weight change at 12 weeks follow up. Several measures of adherence were also used, including 24hr total urine collections. Results: 41 participants were randomized to the intervention group and 43 to the comparator group. The water preloading group lost -1.3kg (95% CI -2.4 to -0.1, p=0.028) more than comparators at follow up. Adjusting for ethnicity, deprivation, age and gender resulted in the intervention group losing -1.2kg (95% CI -2.4 to 0.07, p=0.063) more than the comparator. Conclusion: There is preliminary evidence that water preloading before main meals leads to a moderate weight loss at follow up. ISRCTN33238158

AB - Objective: To investigate the efficacy of water preloading before meals as a weight loss strategy for adults with obesity. Methods: Two group randomized controlled trial conducted in Birmingham, England. 84 adults with obesity were recruited from general practices. All participants were given a face to face weight management consultation at baseline (30 minutes) and a follow-up telephone consultation at two weeks (10 minutes). At baseline participants were randomized to either drinking 500mls of water 30 minutes before their main meals or an attention control group where participants were asked to imagine their stomach was full before meals. The primary outcome was weight change at 12 weeks follow up. Several measures of adherence were also used, including 24hr total urine collections. Results: 41 participants were randomized to the intervention group and 43 to the comparator group. The water preloading group lost -1.3kg (95% CI -2.4 to -0.1, p=0.028) more than comparators at follow up. Adjusting for ethnicity, deprivation, age and gender resulted in the intervention group losing -1.2kg (95% CI -2.4 to 0.07, p=0.063) more than the comparator. Conclusion: There is preliminary evidence that water preloading before main meals leads to a moderate weight loss at follow up. ISRCTN33238158

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