Abstract
Radiation damping induced by the strong water magnetization in Z-spectroscopy experiments can be sufficient to perturb significantly the resultant Z-spectrum. With a probe tuned to exact electrical resonance the effects are relatively straightforward, narrowing the central feature of the Z-spectrum. Where, as is commonly the case, the probe is tuned sufficiently well to give optimum signal-to-noise ratio and radiofrequency field strength but is not at exact resonance, radiation damping introduces an unexpected asymmetry into the Z-spectrum. This has the potential to complicate the use of Z-spectrum asymmetry to study chemical exchange, for example in the estimation of pH in vivo. (c) 2006 Elsevier Inc. All rights reserved.
Original language | English |
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Pages (from-to) | 203-212 |
Number of pages | 10 |
Journal | Journal of Magnetic Resonance |
Volume | 183 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1 Dec 2006 |
Keywords
- chemical exchange
- radiation damping
- magnetization transfer
- probe tuning
- Z-spectroscopy