Effect of photon energy in collagen generation by interstitial low level laser stimulation

Eunkwon Jun, Myungjin Ha, Sangyeob Lee, Edalat Radfar, Jihoon Park, Byungjo Jung

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Although the mechanism of low level laser therapy (LLLT) is unclear, many studies demonstrated the positive clinical performance of LLLT for skin rejuvenation. An increase in dermal collagen plays an important role in skin rejuvenation and wound healing. This study aimed to investigate collagen generation after interstitial low level laser stimulation (ILLS). Rabbits were divided into two groups: surfacing irradiation and minimally invasive irradiation. 660nm diode laser of 20mW with 10J, 13J and 15J was applied to the backside of rabbits. Collagen formation was evaluated with ultrasound skin scanner every 12 hours. Results shows that ILLS groups have denser collagen density than surfacing groups.

Original languageEnglish
Title of host publicationMechanisms for Low-Light Therapy X
EditorsMichael R. Hamblin, Praveen Arany, James D. Carroll
PublisherSociety of Photo-Optical Instrumentation Engineers
ISBN (Electronic)9781628413991
Publication statusPublished - 2015
EventMechanisms for Low-Light Therapy X - San Francisco, United States
Duration: 7 Feb 20158 Feb 2015

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceMechanisms for Low-Light Therapy X
Country/TerritoryUnited States
CitySan Francisco

Bibliographical note

Publisher Copyright:
© 2015 SPIE.

Copyright 2015 Elsevier B.V., All rights reserved.


  • irradiation
  • low level laser
  • minimally
  • surfacing

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging


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