TY - JOUR
T1 - Effect of age on exercise-induced alterations in cognitive executive function
T2 - Relationship to cerebral perfusion
AU - Lucas, S.J.E.
AU - Murrell, C.J.
AU - Thomas, K.N.
AU - Cotter, J.D.
AU - Ainslie, P.N.
AU - Franz, E.A.
PY - 2012/8/1
Y1 - 2012/8/1
N2 - Regular exercise improves the age-related decline in cerebral blood flow (CBF) and is associated with improved cognitive function; however, less is known about the direct relationship between CBF and cognitive function. We examined the influence of healthy aging on the capability of acute exercise to improve cognition, and whether exercise-induced improvements in cognition are related to CBF and cortical hemodynamics. Middle cerebral artery blood flow velocity (MCAv; Doppler) and cortical hemodynamics (NIRS) were measured in 13 young (24±5 y) and 9 older (62±3 y) participants at rest and during cycling at 30% and 70% of heart rate range (HRR). Cognitive performance was assessed using a computer-adapted Stroop task (i.e., test of executive function cognition) at rest and during exercise. Average response times on the Stroop task were slower for the older compared to younger group for both simple and difficult tasks (P
AB - Regular exercise improves the age-related decline in cerebral blood flow (CBF) and is associated with improved cognitive function; however, less is known about the direct relationship between CBF and cognitive function. We examined the influence of healthy aging on the capability of acute exercise to improve cognition, and whether exercise-induced improvements in cognition are related to CBF and cortical hemodynamics. Middle cerebral artery blood flow velocity (MCAv; Doppler) and cortical hemodynamics (NIRS) were measured in 13 young (24±5 y) and 9 older (62±3 y) participants at rest and during cycling at 30% and 70% of heart rate range (HRR). Cognitive performance was assessed using a computer-adapted Stroop task (i.e., test of executive function cognition) at rest and during exercise. Average response times on the Stroop task were slower for the older compared to younger group for both simple and difficult tasks (P
UR - http://www.scopus.com/inward/record.url?partnerID=yv4JPVwI&eid=2-s2.0-84863095227&md5=d59cae912b676589c237b0d19983be7b
U2 - 10.1016/j.exger.2011.12.002
DO - 10.1016/j.exger.2011.12.002
M3 - Article
AN - SCOPUS:84863095227
SN - 0531-5565
VL - 47
SP - 541
EP - 551
JO - Experimental gerontology
JF - Experimental gerontology
IS - 8
ER -