EEG frequency during spike-wave discharges may predict treatment outcome in patients with idiopathic generalized epilepsies

O. Benjamin, P. Colvin, M. Kibuuka, G. Alarcõn, M.P. Richardson, J.R. Terry

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

We report findings concerning the relationship between electroencephalography (EEG) frequency during spike-and-wave discharges (SWDs) and response to treatment in 21 patients with idiopathic generalized epilepsy (IGE). We studied patients whose EEG contained SWDs lasting at least 4 s. Among these patients, two groups could be distinguished on the basis of a subtle difference in EEG frequency during the first 2 s of the burst. The two groups differed markedly in their clinical response to medication, with the group becoming seizure-free during the next 1–2 years showing a spike-wave onset frequency of >3.2 Hz, and those not seizure-free
Original languageEnglish
Pages (from-to)e45-e48
JournalEpilepsia
Volume52
Issue number6
DOIs
Publication statusPublished - 2011

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