Earlier intervention for acute kidney injury: Evaluation of an outreach service and a long-term follow-up

Mark E. Thomas*, Alice Sitch, Jyoti Baharani, George Dowswell

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    21 Citations (Scopus)


    Background There have been few studies of earlier systematic intervention to reduce the impact of acute kidney injury (AKI). In 2009, we piloted an AKI outreach service with a before and after study, and we report on the study and its longer-term follow-up. Methods AKI patients were identified using a laboratory delta check for creatinine of 75%. In the 4-week before phase patients received standard care. In a consecutive 7-week after phase an outreach team of nephrology doctors and nurses reviewed all alerts twice daily, 5 days a week. The primary clinical team caring for the patient was called to be given advice on AKI care. Results There were 157 and 251 patients in the before and after groups, respectively, who were comparable in their characteristics. The mean age was 70 years in both groups and ∼80% of each group were admitted to the hospital. In the after group, the Outreach telephone call was successful in 88%, at a median of 14 h. Substantial numbers of recommendations were made, largely related to fluid balance, investigations and medication use. Survival showed an immediate non-significant improvement in the after group, but converged at about 4 years. Conclusion Outreach shows potential to improve outcomes in AKI. In order to achieve this it seems likely that at least a five-day per week service will be needed to assist good renal and general medical care for this vulnerable group.

    Original languageEnglish
    Pages (from-to)239-244
    Number of pages6
    JournalNephrology, Dialysis, Transplantation
    Issue number2
    Publication statusPublished - 1 Jan 2015


    • acute kidney injury
    • clinical laboratory information systems
    • creatinine
    • early intervention

    ASJC Scopus subject areas

    • Nephrology
    • Transplantation


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