Keyphrases
Cell Death
100%
Endoplasmic Reticulum
100%
Mitochondria
100%
Stable Analogue
100%
Dual Mechanism
100%
Mitochondrium
100%
Sarcoplasmic Reticulum Ca2+-ATPase
37%
Thapsigargin
25%
Calcium Release
25%
Bcl-2 Family Proteins
25%
Small Molecules
25%
Caspase-9 Activation
25%
Endoplasmic Reticulum Calcium
25%
Bcl-2 Antagonist
25%
Activating Transcription Factor 4 (ATF4)
25%
Tumor Cells
12%
Mode of Action
12%
Well-defined
12%
Enzymatic Activity
12%
Protective Effect
12%
Mechanism of Action
12%
Malignant Cells
12%
Leukemic Cells
12%
Anti-apoptotic
12%
Chloro
12%
Nitrobenzenesulfonamides
12%
Promote Apoptosis
12%
Inducible Transcription Factor
12%
Anti-apoptotic Bcl-2
12%
Targeting Mechanism
12%
Pan-caspase Inhibitor
12%
Apoptotic Resistance
12%
Stress-inducible
12%
Induced Loss
12%
Induced Cell Death
12%
Benzoyl
12%
Endoplasmic Reticulum Stress (ER stress)
12%
Mitochondrial Pathway
12%
Trifluoromethyl Ketones
12%
Dimethylamino
12%
Mitochondrial Transmembrane Potential
12%
Dual Targeting
12%
ABT-737
12%
Inositol Trisphosphate Receptor
12%
Biphenyl-2
12%
Pharmacology, Toxicology and Pharmaceutical Science
Calcium Ion
100%
Antiapoptotic
66%
Thapsigargin
66%
Adenosine Triphosphatase
66%
Caspase 9
66%
Receptor
33%
Neoplasm
33%
Caspase Inhibitor
33%
Adenosine Triphosphatase Inhibitor
33%
Biphenyl
33%
Activating Transcription Factor 4
33%
Inositol Trisphosphate
33%
Piperazine
33%