Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study

József Zsiros; Laurence Brugieres; Penelope Brock; Derek Roebuck; Rudolf Maibach; Arthur Zimmermann; Margaret Childs; Daniele Pariente; Veronique Laithier; Jean-Bernard Otte; Sophie Branchereau; Daniel Aronson; Arun Rangaswami; Milind Ronghe; Michela Casanova; Michael Sullivan; Bruce Morland; Piotr Czauderna; Giorgio Perilongo; International Childhood Liver Tumours Strategy Group (SIOPEL)

doi:10.1016/S1470-2045(13)70272-9

Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study

József Zsiros
, Laurence Brugieres
, Penelope Brock
, Derek Roebuck
, Rudolf Maibach
, Arthur Zimmermann
, Margaret Childs
, Daniele Pariente
, Veronique Laithier
, Jean-Bernard Otte
, Sophie Branchereau
, Daniel Aronson
, Arun Rangaswami
, Milind Ronghe
, Michela Casanova
, Michael Sullivan
, Bruce Morland
, Piotr Czauderna
, Giorgio Perilongo
, International Childhood Liver Tumours Strategy Group (SIOPEL)

Cancer and Genomic Sciences

Research output: Contribution to journal › Article › peer-review

136 Citations (Scopus)

Abstract

The objective of this study was to establish the efficacy and safety of a new treatment regimen consisting of dose-dense cisplatin-based chemotherapy and radical surgery in children with high-risk hepatoblastoma.

Original language	English
Pages (from-to)	834-842
Journal	The Lancet Oncology
Volume	14
Issue number	9
DOIs	https://doi.org/10.1016/S1470-2045(13)70272-9
Publication status	Published - 3 Jul 2013

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Zsiros, J., Brugieres, L., Brock, P., Roebuck, D., Maibach, R., Zimmermann, A., Childs, M., Pariente, D., Laithier, V., Otte, J.-B., Branchereau, S., Aronson, D., Rangaswami, A., Ronghe, M., Casanova, M., Sullivan, M., Morland, B., Czauderna, P., Perilongo, G., & International Childhood Liver Tumours Strategy Group (SIOPEL) (2013). Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study. The Lancet Oncology, 14(9), 834-842. https://doi.org/10.1016/S1470-2045(13)70272-9

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title = "Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study",

abstract = "The objective of this study was to establish the efficacy and safety of a new treatment regimen consisting of dose-dense cisplatin-based chemotherapy and radical surgery in children with high-risk hepatoblastoma.",

author = "J{\'o}zsef Zsiros and Laurence Brugieres and Penelope Brock and Derek Roebuck and Rudolf Maibach and Arthur Zimmermann and Margaret Childs and Daniele Pariente and Veronique Laithier and Jean-Bernard Otte and Sophie Branchereau and Daniel Aronson and Arun Rangaswami and Milind Ronghe and Michela Casanova and Michael Sullivan and Bruce Morland and Piotr Czauderna and Giorgio Perilongo and \{International Childhood Liver Tumours Strategy Group (SIOPEL)\}",

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doi = "10.1016/S1470-2045(13)70272-9",

language = "English",

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Zsiros, J, Brugieres, L, Brock, P, Roebuck, D, Maibach, R, Zimmermann, A, Childs, M, Pariente, D, Laithier, V, Otte, J-B, Branchereau, S, Aronson, D, Rangaswami, A, Ronghe, M, Casanova, M, Sullivan, M, Morland, B, Czauderna, P, Perilongo, G & International Childhood Liver Tumours Strategy Group (SIOPEL) 2013, 'Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study', The Lancet Oncology, vol. 14, no. 9, pp. 834-842. https://doi.org/10.1016/S1470-2045(13)70272-9

TY - JOUR

T1 - Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4)

T2 - a prospective, single-arm, feasibility study

AU - Zsiros, József

AU - Brugieres, Laurence

AU - Brock, Penelope

AU - Roebuck, Derek

AU - Maibach, Rudolf

AU - Zimmermann, Arthur

AU - Childs, Margaret

AU - Pariente, Daniele

AU - Laithier, Veronique

AU - Otte, Jean-Bernard

AU - Branchereau, Sophie

AU - Aronson, Daniel

AU - Rangaswami, Arun

AU - Ronghe, Milind

AU - Casanova, Michela

AU - Sullivan, Michael

AU - Morland, Bruce

AU - Czauderna, Piotr

AU - Perilongo, Giorgio

AU - International Childhood Liver Tumours Strategy Group (SIOPEL)

PY - 2013/7/3

Y1 - 2013/7/3

N2 - The objective of this study was to establish the efficacy and safety of a new treatment regimen consisting of dose-dense cisplatin-based chemotherapy and radical surgery in children with high-risk hepatoblastoma.

AB - The objective of this study was to establish the efficacy and safety of a new treatment regimen consisting of dose-dense cisplatin-based chemotherapy and radical surgery in children with high-risk hepatoblastoma.

U2 - 10.1016/S1470-2045(13)70272-9

DO - 10.1016/S1470-2045(13)70272-9

M3 - Article

C2 - 23831416

SN - 1470-2045

VL - 14

SP - 834

EP - 842

JO - The Lancet Oncology

JF - The Lancet Oncology

IS - 9

ER -

Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study

Abstract

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