Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study

József Zsiros; Laurence Brugieres; Penelope Brock; Derek Roebuck; Rudolf Maibach; Arthur Zimmermann; Margaret Childs; Daniele Pariente; Veronique Laithier; Jean-Bernard Otte; Sophie Branchereau; Daniel Aronson; Arun Rangaswami; Milind Ronghe; Michela Casanova; Michael Sullivan; Bruce Morland; Piotr Czauderna; Giorgio Perilongo; International Childhood Liver Tumours Strategy Group (SIOPEL)

doi:10.1016/S1470-2045(13)70272-9

Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study

József Zsiros, Laurence Brugieres, Penelope Brock, Derek Roebuck, Rudolf Maibach, Arthur Zimmermann, Margaret Childs, Daniele Pariente, Veronique Laithier, Jean-Bernard Otte, Sophie Branchereau, Daniel Aronson, Arun Rangaswami, Milind Ronghe, Michela Casanova, Michael Sullivan, Bruce Morland, Piotr Czauderna, Giorgio Perilongo, International Childhood Liver Tumours Strategy Group (SIOPEL)

Cancer and Genomic Sciences

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Abstract

The objective of this study was to establish the efficacy and safety of a new treatment regimen consisting of dose-dense cisplatin-based chemotherapy and radical surgery in children with high-risk hepatoblastoma.

Original language	English
Pages (from-to)	834-842
Journal	The Lancet Oncology
Volume	14
Issue number	9
DOIs	https://doi.org/10.1016/S1470-2045(13)70272-9
Publication status	Published - 3 Jul 2013

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Zsiros, J., Brugieres, L., Brock, P., Roebuck, D., Maibach, R., Zimmermann, A., Childs, M., Pariente, D., Laithier, V., Otte, J-B., Branchereau, S., Aronson, D., Rangaswami, A., Ronghe, M., Casanova, M., Sullivan, M., Morland, B., Czauderna, P., Perilongo, G., & International Childhood Liver Tumours Strategy Group (SIOPEL) (2013). Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study. The Lancet Oncology, 14(9), 834-842. https://doi.org/10.1016/S1470-2045(13)70272-9

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title = "Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study",

abstract = "The objective of this study was to establish the efficacy and safety of a new treatment regimen consisting of dose-dense cisplatin-based chemotherapy and radical surgery in children with high-risk hepatoblastoma.",

author = "J{\'o}zsef Zsiros and Laurence Brugieres and Penelope Brock and Derek Roebuck and Rudolf Maibach and Arthur Zimmermann and Margaret Childs and Daniele Pariente and Veronique Laithier and Jean-Bernard Otte and Sophie Branchereau and Daniel Aronson and Arun Rangaswami and Milind Ronghe and Michela Casanova and Michael Sullivan and Bruce Morland and Piotr Czauderna and Giorgio Perilongo and {International Childhood Liver Tumours Strategy Group (SIOPEL)}",

year = "2013",

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doi = "10.1016/S1470-2045(13)70272-9",

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Zsiros, J, Brugieres, L, Brock, P, Roebuck, D, Maibach, R, Zimmermann, A, Childs, M, Pariente, D, Laithier, V, Otte, J-B, Branchereau, S, Aronson, D, Rangaswami, A, Ronghe, M, Casanova, M, Sullivan, M, Morland, B, Czauderna, P, Perilongo, G & International Childhood Liver Tumours Strategy Group (SIOPEL) 2013, 'Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study', The Lancet Oncology, vol. 14, no. 9, pp. 834-842. https://doi.org/10.1016/S1470-2045(13)70272-9

TY - JOUR

T1 - Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4)

T2 - a prospective, single-arm, feasibility study

AU - Zsiros, József

AU - Brugieres, Laurence

AU - Brock, Penelope

AU - Roebuck, Derek

AU - Maibach, Rudolf

AU - Zimmermann, Arthur

AU - Childs, Margaret

AU - Pariente, Daniele

AU - Laithier, Veronique

AU - Otte, Jean-Bernard

AU - Branchereau, Sophie

AU - Aronson, Daniel

AU - Rangaswami, Arun

AU - Ronghe, Milind

AU - Casanova, Michela

AU - Sullivan, Michael

AU - Morland, Bruce

AU - Czauderna, Piotr

AU - Perilongo, Giorgio

AU - International Childhood Liver Tumours Strategy Group (SIOPEL)

PY - 2013/7/3

Y1 - 2013/7/3

N2 - The objective of this study was to establish the efficacy and safety of a new treatment regimen consisting of dose-dense cisplatin-based chemotherapy and radical surgery in children with high-risk hepatoblastoma.

AB - The objective of this study was to establish the efficacy and safety of a new treatment regimen consisting of dose-dense cisplatin-based chemotherapy and radical surgery in children with high-risk hepatoblastoma.

U2 - 10.1016/S1470-2045(13)70272-9

DO - 10.1016/S1470-2045(13)70272-9

M3 - Article

C2 - 23831416

SN - 1470-2045

VL - 14

SP - 834

EP - 842

JO - The Lancet Oncology

JF - The Lancet Oncology

IS - 9

ER -

Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study

Abstract

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