Do affective or dissociative symptoms mediate the association between childhood sexual trauma and transition to psychosis in an ultra-high risk cohort?

Andrew Thompson; Steven Marwaha; Barnaby Nelson; Stephen J Wood; Patrick D McGorry; Alison R Yung; Ashleigh Lin

doi:10.1016/j.psychres.2016.01.017

Do affective or dissociative symptoms mediate the association between childhood sexual trauma and transition to psychosis in an ultra-high risk cohort?

Andrew Thompson
, Steven Marwaha
, Barnaby Nelson
, Stephen J Wood
, Patrick D McGorry
, Alison R Yung
, Ashleigh Lin

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

463 Downloads (Pure)

Abstract

We have previously reported an association between childhood sexual trauma and transition to psychosis in an Ultra High Risk (UHR) population. We aimed to investigate if this association was mediated by affective or dissociative symptoms. Data were from a large UHR for psychosis cohort study. None of the potential mediators (depression, anxiety, dissociation, mood swings and mania, assessed by the HAM-D, HAM-A and the CAARMS symptom scales) significantly mediated the total association between sexual abuse scores and transition. At the point of transition, the mechanistic pathway from sexual trauma to psychosis does not appear to operate through affective symptoms.

Original language	English
Pages (from-to)	182-185
Number of pages	4
Journal	Psychiatry Research
Volume	236
DOIs	https://doi.org/10.1016/j.psychres.2016.01.017 https://doi.org/10.1016/j.psychres.2016.01.017
Publication status	Published - 28 Feb 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 16 Peace, Justice and Strong Institutions

Keywords

Adolescent
Adult
Affective Symptoms/psychology
Anxiety/psychology
Bipolar Disorder/psychology
Child
Child Abuse, Sexual/psychology
Cohort Studies
Depression/psychology
Dissociative Disorders/psychology
Female
Humans
Male
Mood Disorders/psychology
Psychotic Disorders/psychology
Risk
Young Adult

Access to Document

Thompson_et_al_Do_affective_or_dissociative_symptoms_Psychiatry_Research_2016Accepted author manuscript, 469 KBLicence: Creative Commons: Attribution-NonCommercial-NoDerivs (CC BY-NC-ND)

http://linkinghub.elsevier.com/retrieve/pii/S0165178115304108

Cite this

Thompson, A., Marwaha, S., Nelson, B., Wood, S. J., McGorry, P. D., Yung, A. R., & Lin, A. (2016). Do affective or dissociative symptoms mediate the association between childhood sexual trauma and transition to psychosis in an ultra-high risk cohort? Psychiatry Research, 236, 182-185. https://doi.org/10.1016/j.psychres.2016.01.017, https://doi.org/10.1016/j.psychres.2016.01.017

@article{a288240e260543b1ad383251efe27ac0,

title = "Do affective or dissociative symptoms mediate the association between childhood sexual trauma and transition to psychosis in an ultra-high risk cohort?",

abstract = "We have previously reported an association between childhood sexual trauma and transition to psychosis in an Ultra High Risk (UHR) population. We aimed to investigate if this association was mediated by affective or dissociative symptoms. Data were from a large UHR for psychosis cohort study. None of the potential mediators (depression, anxiety, dissociation, mood swings and mania, assessed by the HAM-D, HAM-A and the CAARMS symptom scales) significantly mediated the total association between sexual abuse scores and transition. At the point of transition, the mechanistic pathway from sexual trauma to psychosis does not appear to operate through affective symptoms. ",

keywords = "Adolescent, Adult, Affective Symptoms/psychology, Anxiety/psychology, Bipolar Disorder/psychology, Child, Child Abuse, Sexual/psychology, Cohort Studies, Depression/psychology, Dissociative Disorders/psychology, Female, Humans, Male, Mood Disorders/psychology, Psychotic Disorders/psychology, Risk, Young Adult",

author = "Andrew Thompson and Steven Marwaha and Barnaby Nelson and Wood, \{Stephen J\} and McGorry, \{Patrick D\} and Yung, \{Alison R\} and Ashleigh Lin",

year = "2016",

month = feb,

day = "28",

doi = "10.1016/j.psychres.2016.01.017",

language = "English",

volume = "236",

pages = "182--185",

journal = "Psychiatry Research",

issn = "01651781",