Diverse Profiles of Anxiety Related Disorders in Fragile X, Cornelia de Lange and Rubinstein–Taybi Syndromes

Hayley Crawford, Jane Waite, Chris Oliver

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)
125 Downloads (Pure)

Abstract

Anxiety disorders are heightened in specific genetic syndromes in comparison to intellectual disability of heterogeneous aetiology. In this study, we described and contrasted anxiety symptomatology in fragile X (FXS), Cornelia de Lange (CdLS) and Rubinstein–Taybi syndromes (RTS), and compared the symptomatology to normative data for typically-developing children and children diagnosed with an anxiety disorder. Scores did not differ between children diagnosed with an anxiety disorder and (a) participants with FXS on social phobia, panic/agoraphobia, physical injury fears, and obsessive–compulsive subscales (b) participants with CdLS on separation anxiety, generalized anxiety, panic/agoraphobia, physical injury fears and obsessive–compulsive subscales, and (c) participants with RTS on panic/agoraphobia and obsessive–compulsive subscales. The results highlight divergent profiles of anxiety symptomatology between these groups.

Original languageEnglish
Pages (from-to)3728–3740
Number of pages13
JournalJournal of Autism and Developmental Disorders
Volume47
Issue number12
Early online date31 Jan 2017
DOIs
Publication statusPublished - Dec 2017

Keywords

  • Anxiety
  • Cornelia de Lange syndrome
  • Fragile X syndrome
  • Genetic syndromes
  • Intellectual disability
  • Rubinstein–Taybi syndrome

ASJC Scopus subject areas

  • Developmental and Educational Psychology

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