Dissemination of IncF plasmids carrying beta-lactamase genes in Gram-negative bacteria from Nigerian hospitals

David Olusoga Ogbolu; Oluwole Adebayo Daini; Afolabi Ogunledun; Oyebode Armstrong Terry Alli; Mark Alexander Webber

Dissemination of IncF plasmids carrying beta-lactamase genes in Gram-negative bacteria from Nigerian hospitals

David Olusoga Ogbolu, Oluwole Adebayo Daini, Afolabi Ogunledun, Oyebode Armstrong Terry Alli, Mark Alexander Webber

Immunology and Immunotherapy

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Production of beta-lactamases is the predominant cause of resistance to beta-lactam antibiotics in Gram-negative bacteria. We investigated the diversity of plasmid-borne beta-lactamase genes and replicon type of the plasmids carrying the respective genes in Gram-negative bacteria recovered from clinical infection in Nigerian hospitals.

Original language	English
Pages (from-to)	382-90
Number of pages	9
Journal	Journal of infection in developing countries
Volume	7
Issue number	5
Publication status	Published - May 2013

Keywords

Anti-Bacterial Agents
Conjugation, Genetic
Cross Infection
DNA, Bacterial
Gene Transfer, Horizontal
Genes, Bacterial
Genetic Variation
Gram-Negative Bacteria
Gram-Negative Bacterial Infections
Hospitals
Humans
Microbial Sensitivity Tests
Multiplex Polymerase Chain Reaction
Nigeria
Plasmids
beta-Lactamases

Cite this

@article{0e2e2f886a5b4e8ca01abb6d2e8e8728,

title = "Dissemination of IncF plasmids carrying beta-lactamase genes in Gram-negative bacteria from Nigerian hospitals",

abstract = "Production of beta-lactamases is the predominant cause of resistance to beta-lactam antibiotics in Gram-negative bacteria. We investigated the diversity of plasmid-borne beta-lactamase genes and replicon type of the plasmids carrying the respective genes in Gram-negative bacteria recovered from clinical infection in Nigerian hospitals.",

keywords = "Anti-Bacterial Agents, Conjugation, Genetic, Cross Infection, DNA, Bacterial, Gene Transfer, Horizontal, Genes, Bacterial, Genetic Variation, Gram-Negative Bacteria, Gram-Negative Bacterial Infections, Hospitals, Humans, Microbial Sensitivity Tests, Multiplex Polymerase Chain Reaction, Nigeria, Plasmids, beta-Lactamases",

author = "Ogbolu, {David Olusoga} and Daini, {Oluwole Adebayo} and Afolabi Ogunledun and {Terry Alli}, {Oyebode Armstrong} and Webber, {Mark Alexander}",

year = "2013",

month = may,

language = "English",

volume = "7",

pages = "382--90",

journal = "Journal of infection in developing countries",

publisher = "Journal of Infection in Developing Countries",

number = "5",

}

TY - JOUR

T1 - Dissemination of IncF plasmids carrying beta-lactamase genes in Gram-negative bacteria from Nigerian hospitals

AU - Ogbolu, David Olusoga

AU - Daini, Oluwole Adebayo

AU - Ogunledun, Afolabi

AU - Terry Alli, Oyebode Armstrong

AU - Webber, Mark Alexander

PY - 2013/5

Y1 - 2013/5

N2 - Production of beta-lactamases is the predominant cause of resistance to beta-lactam antibiotics in Gram-negative bacteria. We investigated the diversity of plasmid-borne beta-lactamase genes and replicon type of the plasmids carrying the respective genes in Gram-negative bacteria recovered from clinical infection in Nigerian hospitals.

AB - Production of beta-lactamases is the predominant cause of resistance to beta-lactam antibiotics in Gram-negative bacteria. We investigated the diversity of plasmid-borne beta-lactamase genes and replicon type of the plasmids carrying the respective genes in Gram-negative bacteria recovered from clinical infection in Nigerian hospitals.

KW - Anti-Bacterial Agents

KW - Conjugation, Genetic

KW - Cross Infection

KW - DNA, Bacterial

KW - Gene Transfer, Horizontal

KW - Genes, Bacterial

KW - Genetic Variation

KW - Gram-Negative Bacteria

KW - Gram-Negative Bacterial Infections

KW - Hospitals

KW - Humans

KW - Microbial Sensitivity Tests

KW - Multiplex Polymerase Chain Reaction

KW - Nigeria

KW - Plasmids

KW - beta-Lactamases

M3 - Article

C2 - 23669427

VL - 7

SP - 382

EP - 390

JO - Journal of infection in developing countries

JF - Journal of infection in developing countries

IS - 5

ER -

Dissemination of IncF plasmids carrying beta-lactamase genes in Gram-negative bacteria from Nigerian hospitals

Abstract

Keywords

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