Partnerships and parenthood have important effects on economic, social and psychological well-being. We provide new long-term analysis of how disability affects both parental status and partnerships. Analysis of the new Life Opportunities Survey, which is based on social model approaches, demonstrates that disabled people are more likely than non-disabled people to face disadvantages in terms of family formation. Disabled people are more likely to remain single over time, although there is lesser evidence of any differences in rates of relationship breakdown for those who enter them. Allied to these conclusions, disabled adults are less likely to form households where there are dependent children. These conclusions are supported by longitudinal results from the British Household Panel Survey.