Diffuse large B-cell lymphoma: the history, current view and new perspectives

P Flodr; P Latalova; M Tichy; Z Kubova; T Papajik; M Svachova; K Vrzalikova; L Radova; M Jarosova; Paul Murray

doi:10.4149/neo_2014_062

Diffuse large B-cell lymphoma: the history, current view and new perspectives

P Flodr, P Latalova, M Tichy, Z Kubova, T Papajik, M Svachova, K Vrzalikova, L Radova, M Jarosova, Paul Murray

Cancer and Genomic Sciences

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

The basic principles of lymphoma classification(s) in general have been widely evolving in a course of decades of years wiht the use of contemporary resources and recent cutting edges in hematooncology on a clinical, morphological and molecular level bring new possibilities not only in improvements of diagnostic and prognostic algorithms and also bear new opportunities in so called targeted and tailored strategies of lymphoma therapy. The pathogenesis and biologic behavior of lymphoproliferations and even lymphomas should be studied in a context of lymphocytic and (neoplastic) lymphoid stage and chronologic development. In a current more complex insight into lymphoproliferations we would like to describe huge heterogeneity of diffuse large B-cell lymphoma in relationship to mandatory WHO classification since 2008 and the next development of knowledge in this field with potential new influence on an advancement of both classification and therapy.

Original language	English
Pages (from-to)	491-504
Number of pages	14
Journal	Neoplasma
Volume	61
Issue number	5
DOIs	https://doi.org/10.4149/neo_2014_062
Publication status	Published - 2014

Keywords

Humans
Lymphoma, Large B-Cell, Diffuse
Prognosis

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10.4149/neo_2014_062

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title = "Diffuse large B-cell lymphoma: the history, current view and new perspectives",

abstract = "The basic principles of lymphoma classification(s) in general have been widely evolving in a course of decades of years wiht the use of contemporary resources and recent cutting edges in hematooncology on a clinical, morphological and molecular level bring new possibilities not only in improvements of diagnostic and prognostic algorithms and also bear new opportunities in so called targeted and tailored strategies of lymphoma therapy. The pathogenesis and biologic behavior of lymphoproliferations and even lymphomas should be studied in a context of lymphocytic and (neoplastic) lymphoid stage and chronologic development. In a current more complex insight into lymphoproliferations we would like to describe huge heterogeneity of diffuse large B-cell lymphoma in relationship to mandatory WHO classification since 2008 and the next development of knowledge in this field with potential new influence on an advancement of both classification and therapy.",

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pages = "491--504",

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T1 - Diffuse large B-cell lymphoma

T2 - the history, current view and new perspectives

AU - Flodr, P

AU - Latalova, P

AU - Tichy, M

AU - Kubova, Z

AU - Papajik, T

AU - Svachova, M

AU - Vrzalikova, K

AU - Radova, L

AU - Jarosova, M

AU - Murray, Paul

PY - 2014

Y1 - 2014

N2 - The basic principles of lymphoma classification(s) in general have been widely evolving in a course of decades of years wiht the use of contemporary resources and recent cutting edges in hematooncology on a clinical, morphological and molecular level bring new possibilities not only in improvements of diagnostic and prognostic algorithms and also bear new opportunities in so called targeted and tailored strategies of lymphoma therapy. The pathogenesis and biologic behavior of lymphoproliferations and even lymphomas should be studied in a context of lymphocytic and (neoplastic) lymphoid stage and chronologic development. In a current more complex insight into lymphoproliferations we would like to describe huge heterogeneity of diffuse large B-cell lymphoma in relationship to mandatory WHO classification since 2008 and the next development of knowledge in this field with potential new influence on an advancement of both classification and therapy.

AB - The basic principles of lymphoma classification(s) in general have been widely evolving in a course of decades of years wiht the use of contemporary resources and recent cutting edges in hematooncology on a clinical, morphological and molecular level bring new possibilities not only in improvements of diagnostic and prognostic algorithms and also bear new opportunities in so called targeted and tailored strategies of lymphoma therapy. The pathogenesis and biologic behavior of lymphoproliferations and even lymphomas should be studied in a context of lymphocytic and (neoplastic) lymphoid stage and chronologic development. In a current more complex insight into lymphoproliferations we would like to describe huge heterogeneity of diffuse large B-cell lymphoma in relationship to mandatory WHO classification since 2008 and the next development of knowledge in this field with potential new influence on an advancement of both classification and therapy.

KW - Humans

KW - Lymphoma, Large B-Cell, Diffuse

KW - Prognosis

U2 - 10.4149/neo_2014_062

DO - 10.4149/neo_2014_062

M3 - Article

C2 - 25030433

SN - 0028-2685

VL - 61

SP - 491

EP - 504

JO - Neoplasma

JF - Neoplasma

IS - 5

ER -

Diffuse large B-cell lymphoma: the history, current view and new perspectives

Abstract

Keywords

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