Differential trends in the rising incidence of endometrial cancer by type: data from a UK population-based registry from 1994 to 2006.

T Evans; O Sany; P Pearmain; Raji Ganesan; Andrew Blann; Sudha Sundar

doi:10.1038/bjc.2011.68

Differential trends in the rising incidence of endometrial cancer by type: data from a UK population-based registry from 1994 to 2006.

T Evans, O Sany, P Pearmain, Raji Ganesan, Andrew Blann, Sudha Sundar

Research output: Contribution to journal › Article

106 Citations (Scopus)

Abstract

Background:Endometrial cancer is the most common gynaecological cancer in the western world, the incidence increasing in the United Kingdom by over 40% since 1993. Two types of endometrial cancer exist - oestrogen-dependent type 1 with good prognosis and non-oestrogen-dependent type 2 with poor prognosis. The histopathological distribution of the increase in endometrial cancer is unknown. This study investigates the observed incidence trends of the two types, the age, stage, and socioeconomic distribution of this increase and survival outcome.Methods:Data were analysed from 6867 women with endometrial cancer registered between 1994 and 2006, at a UK population-based cancer registry.Results:Increased endometrial cancer incidence is confined to type 1 cancers with a significant increase in age standardised incidence rate (ASR) from 12.0 per 100 000 (confidence interval (CI) 10.7-13.2) in 1994 to 16.3 per 100 000 (CI 14.9-17.7), P0.05. Increase in type 1 cancer is most marked in age groups 60-69 years (P

Original language	English
Pages (from-to)	1505-1510
Number of pages	6
Journal	British Journal of Cancer
Volume	104
Issue number	9
DOIs	https://doi.org/10.1038/bjc.2011.68
Publication status	Published - 26 Apr 2011

Bibliographical note

Role – I conceived the study and wrote the paper. This paper showed for the first time, that the nearly 50% increase in endometrial cancer incidence over the last decade is confined to obesity driven Type 1 endometrial cancer. This paper is cited in CRUK webpage on uterine cancer. http://www.cancerresearchuk.org/cancer-info/cancerstats/types/uterus/incidence/. Citations - 45

Additional ‘best output’ for this application

Keywords

endometrial cancer
type 1

ASJC Scopus subject areas

Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1038/bjc.2011.68

Cite this

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title = "Differential trends in the rising incidence of endometrial cancer by type: data from a UK population-based registry from 1994 to 2006.",

abstract = "Background:Endometrial cancer is the most common gynaecological cancer in the western world, the incidence increasing in the United Kingdom by over 40% since 1993. Two types of endometrial cancer exist - oestrogen-dependent type 1 with good prognosis and non-oestrogen-dependent type 2 with poor prognosis. The histopathological distribution of the increase in endometrial cancer is unknown. This study investigates the observed incidence trends of the two types, the age, stage, and socioeconomic distribution of this increase and survival outcome.Methods:Data were analysed from 6867 women with endometrial cancer registered between 1994 and 2006, at a UK population-based cancer registry.Results:Increased endometrial cancer incidence is confined to type 1 cancers with a significant increase in age standardised incidence rate (ASR) from 12.0 per 100 000 (confidence interval (CI) 10.7-13.2) in 1994 to 16.3 per 100 000 (CI 14.9-17.7), P0.05. Increase in type 1 cancer is most marked in age groups 60-69 years (P",

keywords = "endometrial cancer, type 1 ",

author = "T Evans and O Sany and P Pearmain and Raji Ganesan and Andrew Blann and Sudha Sundar",

note = "Role – I conceived the study and wrote the paper. This paper showed for the first time, that the nearly 50% increase in endometrial cancer incidence over the last decade is confined to obesity driven Type 1 endometrial cancer. This paper is cited in CRUK webpage on uterine cancer. http://www.cancerresearchuk.org/cancer-info/cancerstats/types/uterus/incidence/. Citations - 45 Additional {\textquoteleft}best output{\textquoteright} for this application ",

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doi = "10.1038/bjc.2011.68",

language = "English",

volume = "104",

pages = "1505--1510",

journal = "British Journal of Cancer",

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T1 - Differential trends in the rising incidence of endometrial cancer by type: data from a UK population-based registry from 1994 to 2006.

AU - Evans, T

AU - Sany, O

AU - Pearmain, P

AU - Ganesan, Raji

AU - Blann, Andrew

AU - Sundar, Sudha

N1 - Role – I conceived the study and wrote the paper. This paper showed for the first time, that the nearly 50% increase in endometrial cancer incidence over the last decade is confined to obesity driven Type 1 endometrial cancer. This paper is cited in CRUK webpage on uterine cancer. http://www.cancerresearchuk.org/cancer-info/cancerstats/types/uterus/incidence/. Citations - 45 Additional ‘best output’ for this application

PY - 2011/4/26

Y1 - 2011/4/26

N2 - Background:Endometrial cancer is the most common gynaecological cancer in the western world, the incidence increasing in the United Kingdom by over 40% since 1993. Two types of endometrial cancer exist - oestrogen-dependent type 1 with good prognosis and non-oestrogen-dependent type 2 with poor prognosis. The histopathological distribution of the increase in endometrial cancer is unknown. This study investigates the observed incidence trends of the two types, the age, stage, and socioeconomic distribution of this increase and survival outcome.Methods:Data were analysed from 6867 women with endometrial cancer registered between 1994 and 2006, at a UK population-based cancer registry.Results:Increased endometrial cancer incidence is confined to type 1 cancers with a significant increase in age standardised incidence rate (ASR) from 12.0 per 100 000 (confidence interval (CI) 10.7-13.2) in 1994 to 16.3 per 100 000 (CI 14.9-17.7), P0.05. Increase in type 1 cancer is most marked in age groups 60-69 years (P

AB - Background:Endometrial cancer is the most common gynaecological cancer in the western world, the incidence increasing in the United Kingdom by over 40% since 1993. Two types of endometrial cancer exist - oestrogen-dependent type 1 with good prognosis and non-oestrogen-dependent type 2 with poor prognosis. The histopathological distribution of the increase in endometrial cancer is unknown. This study investigates the observed incidence trends of the two types, the age, stage, and socioeconomic distribution of this increase and survival outcome.Methods:Data were analysed from 6867 women with endometrial cancer registered between 1994 and 2006, at a UK population-based cancer registry.Results:Increased endometrial cancer incidence is confined to type 1 cancers with a significant increase in age standardised incidence rate (ASR) from 12.0 per 100 000 (confidence interval (CI) 10.7-13.2) in 1994 to 16.3 per 100 000 (CI 14.9-17.7), P0.05. Increase in type 1 cancer is most marked in age groups 60-69 years (P

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KW - type 1

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VL - 104

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EP - 1510

JO - British Journal of Cancer

JF - British Journal of Cancer

IS - 9

ER -

Differential trends in the rising incidence of endometrial cancer by type: data from a UK population-based registry from 1994 to 2006.

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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