Differential contributions of monocyte- and platelet-derived microparticles towards thrombin generation and fibrin formation and stability

M M Aleman; C Gardiner; P Harrison; A S Wolberg

doi:10.1111/j.1538-7836.2011.04488.x

Differential contributions of monocyte- and platelet-derived microparticles towards thrombin generation and fibrin formation and stability

M M Aleman
, C Gardiner
, P Harrison
, A S Wolberg

Immunology and Immunotherapy

Research output: Contribution to journal › Article › peer-review

121 Citations (Scopus)

Abstract

Microparticles (MPs) are sub-micron vesicles shed by activated or apoptotic cells, including platelets and monocytes. Increased circulating MPs are associated with thrombosis; however, their role in thrombogenesis is poorly understood.

Original language	English
Pages (from-to)	2251-61
Number of pages	11
Journal	Journal of thrombosis and haemostasis : JTH
Volume	9
Issue number	11
DOIs	https://doi.org/10.1111/j.1538-7836.2011.04488.x
Publication status	Published - Nov 2011

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10.1111/j.1538-7836.2011.04488.x

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title = "Differential contributions of monocyte- and platelet-derived microparticles towards thrombin generation and fibrin formation and stability",

abstract = "Microparticles (MPs) are sub-micron vesicles shed by activated or apoptotic cells, including platelets and monocytes. Increased circulating MPs are associated with thrombosis; however, their role in thrombogenesis is poorly understood.",

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AU - Gardiner, C

AU - Harrison, P

AU - Wolberg, A S

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N2 - Microparticles (MPs) are sub-micron vesicles shed by activated or apoptotic cells, including platelets and monocytes. Increased circulating MPs are associated with thrombosis; however, their role in thrombogenesis is poorly understood.

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JO - Journal of thrombosis and haemostasis : JTH

JF - Journal of thrombosis and haemostasis : JTH

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Differential contributions of monocyte- and platelet-derived microparticles towards thrombin generation and fibrin formation and stability

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