This is the protocol for a review and there is no abstract. The objectives are as follows: To determine the diagnostic accuracy of pulse oximetry as a screening method for the detection of critical congenital heart defects in asymptomatic newborn infants. Diagnostic accuracy is described by the proportion of asymptomatic newborn infants with CCHD detected by a positive pulse oximetry result (sensitivity), and the proportion of asymptomatic newborn infants with a negative pulse oximetry result who did not have CCHD (specificity). To assess potential sources of heterogeneity including: study design: retrospective vs prospective design, consecutive vs non consecutive series timing of testing: < 24 hours vs ≥ 24 hours after birth site of testing: right hand and foot (pre-ductal and post-ductal) vs foot only (post-ductal) oxygen saturation: functional vs fractional characteristics of the population: antenatal screening.
Bibliographical noteFunding Information:
• CIBERESP, Spain. CIBER Epidemiology and Public Heath • Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, USA. Editorial support of the Cochrane Neonatal Review Group has been funded with Federal funds from the Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Department of Health and Human Services, USA, under Contract No. HHSN275201100016C
© 2015 The Cochrane Collaboration.
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ASJC Scopus subject areas
- Pharmacology (medical)