Abstract
Two quantitative microdialysis methods were used to determine the extracellular concentration of glycine in the dorsal spinal cord of halothane-anaesthetised rats. Extracellular glycine determined by zero net flux was 2.6+/-0.3 microM and by the zero flow method was 3.3+/-0.3 microM. For comparison the glycine content of cerebrospinal fluid was determined to be 6.4+/-1.1 microM. There was no correlation between the extracellular and the cerebrospinal fluid concentrations.
Original language | English |
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Pages (from-to) | 192-194 |
Number of pages | 3 |
Journal | Brain Research |
Volume | 910 |
Issue number | 1-2 |
DOIs | |
Publication status | Published - 10 Aug 2001 |
Keywords
- extracellular concentration
- quantitative microdialysis
- glycine
- spinal cord dorsal horn
- glycine transporter