Detergent-free isolation, characterization, and functional reconstitution of a tetrameric K
              +
              channel: The power of native nanodiscs

Jonas M. Dörr; Martijn C. Koorengevel; Marre Schäfer; Alexander V. Prokofyev; Stefan Scheidelaar; Elwin A. W. Van Der Cruijsen; Timothy R. Dafforn; Marc Baldus; J. Antoinette Killian

doi:10.1073/pnas.1416205112

Detergent-free isolation, characterization, and functional reconstitution of a tetrameric K + channel: The power of native nanodiscs

Jonas M. Dörr
, Martijn C. Koorengevel
, Marre Schäfer
, Alexander V. Prokofyev
, Stefan Scheidelaar
, Elwin A. W. Van Der Cruijsen
, Timothy R. Dafforn
, Marc Baldus
, J. Antoinette Killian

Biosciences

Research output: Contribution to journal › Article › peer-review

177 Citations (Scopus)

Original language	English
Pages (from-to)	18607-18612
Journal	National Academy of Sciences. Proceedings
Volume	111
Issue number	52
DOIs	https://doi.org/10.1073/pnas.1416205112
Publication status	Published - 30 Dec 2014

Access to Document

10.1073/pnas.1416205112

http://www.pnas.org/lookup/doi/10.1073/pnas.1416205112

The Use Of Novel Polymer-Lipid Nanoparticles To Study G-Protein-Coupled Receptor Activation And Dynamics.
Wheatley, M. (Principal Investigator) & Dafforn, T. (Co-Investigator)
Biotechnology & Biological Sciences Research Council
1/01/12 → 31/12/14
Project: Research Councils
An amphipathic nanostructure to extract, stabilze and purify hydrophopic proteins.
Dafforn, T. (Principal Investigator)
Biotechnology & Biological Sciences Research Council
1/05/09 → 30/04/12
Project: Research Councils

Cite this

Dörr, J. M., Koorengevel, M. C., Schäfer, M., Prokofyev, A. V., Scheidelaar, S., Van Der Cruijsen, E. A. W., Dafforn, T. R., Baldus, M., & Killian, J. A. (2014). Detergent-free isolation, characterization, and functional reconstitution of a tetrameric K + channel: The power of native nanodiscs. National Academy of Sciences. Proceedings, 111(52), 18607-18612. https://doi.org/10.1073/pnas.1416205112

@article{07b878a7b4984e0d91c08ef5641c781b,

title = "Detergent-free isolation, characterization, and functional reconstitution of a tetrameric K + channel: The power of native nanodiscs",

author = "D{\"o}rr, \{Jonas M.\} and Koorengevel, \{Martijn C.\} and Marre Sch{\"a}fer and Prokofyev, \{Alexander V.\} and Stefan Scheidelaar and \{Van Der Cruijsen\}, \{Elwin A. W.\} and Dafforn, \{Timothy R.\} and Marc Baldus and Killian, \{J. Antoinette\}",

year = "2014",

month = dec,

day = "30",

doi = "10.1073/pnas.1416205112",

language = "English",

volume = "111",

pages = "18607--18612",

journal = "National Academy of Sciences. Proceedings",

issn = "0027-8424",

publisher = "National Academy of Sciences",

number = "52",

}

Dörr, JM, Koorengevel, MC, Schäfer, M, Prokofyev, AV, Scheidelaar, S, Van Der Cruijsen, EAW, Dafforn, TR, Baldus, M & Killian, JA 2014, 'Detergent-free isolation, characterization, and functional reconstitution of a tetrameric K + channel: The power of native nanodiscs', National Academy of Sciences. Proceedings, vol. 111, no. 52, pp. 18607-18612. https://doi.org/10.1073/pnas.1416205112

Detergent-free isolation, characterization, and functional reconstitution of a tetrameric K + channel: The power of native nanodiscs. / Dörr, Jonas M.; Koorengevel, Martijn C.; Schäfer, Marre et al.
In: National Academy of Sciences. Proceedings, Vol. 111, No. 52, 30.12.2014, p. 18607-18612.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Detergent-free isolation, characterization, and functional reconstitution of a tetrameric K + channel: The power of native nanodiscs

AU - Dörr, Jonas M.

AU - Koorengevel, Martijn C.

AU - Schäfer, Marre

AU - Prokofyev, Alexander V.

AU - Scheidelaar, Stefan

AU - Van Der Cruijsen, Elwin A. W.

AU - Dafforn, Timothy R.

AU - Baldus, Marc

AU - Killian, J. Antoinette

PY - 2014/12/30

Y1 - 2014/12/30

U2 - 10.1073/pnas.1416205112

DO - 10.1073/pnas.1416205112

M3 - Article

SN - 0027-8424

VL - 111

SP - 18607

EP - 18612

JO - National Academy of Sciences. Proceedings

JF - National Academy of Sciences. Proceedings

IS - 52

ER -

Detergent-free isolation, characterization, and functional reconstitution of a tetrameric K + channel: The power of native nanodiscs

Access to Document

Projects

The Use Of Novel Polymer-Lipid Nanoparticles To Study G-Protein-Coupled Receptor Activation And Dynamics.

An amphipathic nanostructure to extract, stabilze and purify hydrophopic proteins.

Cite this