Dental regeneration and materials - a partnership

Anthony Smith, Philip Lumley, Phillip Tomson, Paul Cooper

Research output: Contribution to journalReview article

36 Citations (Scopus)


Considerable focus on the biocompatibility of dental materials over the last three decades has provided a platform for a wealth of studies on the cellular and molecular responses of the cells of the pulp to injury, both from the disease process and from subsequent restorative intervention. These studies have been fundamental to understanding not only how we can achieve a biocompatible response during restoration of dental disease but also how we can exploit the pulpal cellular responses to achieve wound healing and tissue regeneration in the dentine-pulp complex. This article examines the responses of the pulp to injury and the events leading to tissue regeneration. As new biologically based regenerative therapies emerge for the dental tissues, it is important that these develop in partnership with more traditional approaches using dental materials.
Original languageEnglish
Pages (from-to)103-108
Number of pages6
JournalClinical Oral Investigations
Issue number2
Publication statusPublished - 1 Jun 2008


  • regeneration
  • bio-active
  • pulp
  • growth factors
  • dentine


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