Decreased breast cancer risk in systemic lupus erythematosus: the search for a genetic basis continues

S Bernatsky; D F Easton; A Dunning; K Michailidou; R Ramsey-Goldman; A E Clarke; W Foulkes; Caroline Gordon

doi:10.1177/0961203312443992

Decreased breast cancer risk in systemic lupus erythematosus: the search for a genetic basis continues

S Bernatsky, D F Easton, A Dunning, K Michailidou, R Ramsey-Goldman, A E Clarke, W Foulkes, Caroline Gordon

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Recent work has demonstrated an important decrease in breast cancers for women with systemic lupus erythematosus (SLE). The reason behind this phenomenon is unknown. Our purpose was to explore whether the single nucleotide polymorphisms (SNPs) predisposing to SLE might be protective against breast cancer (in women in the general population).

Original language	English
Pages (from-to)	896-9
Number of pages	4
Journal	Lupus
Volume	21
Issue number	8
DOIs	https://doi.org/10.1177/0961203312443992
Publication status	Published - Jul 2012

Keywords

Alleles
Breast Neoplasms
European Continental Ancestry Group
Female
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans
Lupus Erythematosus, Systemic
Odds Ratio
Polymorphism, Single Nucleotide
Risk Factors

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1177/0961203312443992

Cite this

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abstract = "Recent work has demonstrated an important decrease in breast cancers for women with systemic lupus erythematosus (SLE). The reason behind this phenomenon is unknown. Our purpose was to explore whether the single nucleotide polymorphisms (SNPs) predisposing to SLE might be protective against breast cancer (in women in the general population).",

keywords = "Alleles, Breast Neoplasms, European Continental Ancestry Group, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Lupus Erythematosus, Systemic, Odds Ratio, Polymorphism, Single Nucleotide, Risk Factors",

author = "S Bernatsky and Easton, {D F} and A Dunning and K Michailidou and R Ramsey-Goldman and Clarke, {A E} and W Foulkes and Caroline Gordon",

year = "2012",

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T1 - Decreased breast cancer risk in systemic lupus erythematosus

T2 - the search for a genetic basis continues

AU - Bernatsky, S

AU - Easton, D F

AU - Dunning, A

AU - Michailidou, K

AU - Ramsey-Goldman, R

AU - Clarke, A E

AU - Foulkes, W

AU - Gordon, Caroline

PY - 2012/7

Y1 - 2012/7

N2 - Recent work has demonstrated an important decrease in breast cancers for women with systemic lupus erythematosus (SLE). The reason behind this phenomenon is unknown. Our purpose was to explore whether the single nucleotide polymorphisms (SNPs) predisposing to SLE might be protective against breast cancer (in women in the general population).

AB - Recent work has demonstrated an important decrease in breast cancers for women with systemic lupus erythematosus (SLE). The reason behind this phenomenon is unknown. Our purpose was to explore whether the single nucleotide polymorphisms (SNPs) predisposing to SLE might be protective against breast cancer (in women in the general population).

KW - Alleles

KW - Breast Neoplasms

KW - European Continental Ancestry Group

KW - Female

KW - Genetic Predisposition to Disease

KW - Genome-Wide Association Study

KW - Humans

KW - Lupus Erythematosus, Systemic

KW - Odds Ratio

KW - Polymorphism, Single Nucleotide

KW - Risk Factors

U2 - 10.1177/0961203312443992

DO - 10.1177/0961203312443992

M3 - Article

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SN - 0961-2033

VL - 21

SP - 896

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JO - Lupus

JF - Lupus

IS - 8

ER -

Decreased breast cancer risk in systemic lupus erythematosus: the search for a genetic basis continues

Abstract

Keywords

UN SDGs

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