Data efficient unsupervised domain adaptation for cross-modality image segmentation

Cheng Ouyang, Konstantinos Kamnitsas, Carlo Biffi, Jinming Duan, Daniel Rueckert

Research output: Chapter in Book/Report/Conference proceedingConference contribution

18 Citations (Scopus)


Deep learning models trained on medical images from a source domain ( e.g. imaging modality) often fail when deployed on images from a different target domain, despite imaging common anatomical structures. Deep unsupervised domain adaptation (UDA) aims to improve the performance of a deep neural network model on a target domain, using solely unlabelled target domain data and labelled source domain data. However, current state-of-the-art methods exhibit reduced performance when target data is scarce. In this work, we introduce a new data efficient UDA method for multi-domain medical image segmentation. The proposed method combines a novel VAE-based feature prior matching, which is data-efficient, and domain adversarial training to learn a shared domain-invariant latent space which is exploited during segmentation. Our method is evaluated on a public multi-modality cardiac image segmentation dataset by adapting from the labelled source domain (3D MRI) to the unlabelled target domain (3D CT). We show that by using only one single unlabelled 3D CT scan, the proposed architecture outperforms the state-of-the-art in the same setting. Finally, we perform ablation studies on prior matching and domain adversarial training to shed light on the theoretical grounding of the proposed method.
Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention – MICCAI 2019
Subtitle of host publication22nd International Conference, Shenzhen, China, October 13–17, 2019, Proceedings, Part II
EditorsDinggang Shen, Tianming Liu, Terry M. Peters, Lawrence H. Staib, Caroline Essert, Sean Zhou, Pew-Thian Yap, Ali Khan
Number of pages9
ISBN (Electronic)978-3-030-32245-8
ISBN (Print)978-3-030-32244-1
Publication statusPublished - 10 Oct 2019

Publication series

NameLecture Notes in Computer Science
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)


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