Cytokeratin expression in adenocarcinomas of the oesophagogastric junction: a comparative study of adenocarcinomas of the distal oesophagus and of the proximal stomach

Philippe Taniere, G Borghi-Scoazec, JC Saurin, C Lombard-Bohas, J Boulez, F Berger, P Hainaut, JY Scoazec

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Abstract

Adenocarcinomas of the esophagogastric junction form a heterogeneous group of tumors. We aimed to evaluate the value of the expression pattern of cytokeratins 7, 19, and 20 for their diagnosis and classification. A total of 85 cases of adenocarcinoma of the distal esophagus and 67 cases of adenocarcinoma of the proximal stomach, defined on strict topographical criteria, were investigated. About 90% of the adenocarcinomas of distal esophagus were positive for cytokeratins 7 and 19, in contrast to
Original languageEnglish
Pages (from-to)1213-1221
Number of pages9
JournalAmerican Journal of Surgical Pathology
Volume26
DOIs
Publication statusPublished - 1 Jan 2002

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