COVID-19: Is There a Link between Alcohol Abuse and SARS-CoV-2-Induced Severe Neurological Manifestations?

Jibran Sualeh Muhammad; Ruqaiyyah Siddiqui; Naveed Ahmed Khan

doi:10.1021/acsptsci.1c00073

COVID-19: Is There a Link between Alcohol Abuse and SARS-CoV-2-Induced Severe Neurological Manifestations?

Jibran Sualeh Muhammad^*, Ruqaiyyah Siddiqui, Naveed Ahmed Khan^*

^*Corresponding author for this work

Biomedical Sciences

Research output: Contribution to journal › Review article › peer-review

Abstract

For the first time, it is shown that severe COVID-19 associated genes (CCR2, DPP9, HSPA1L, TYK2, OAS1, ACE2, and TMPRSS2) were also upregulated in the brain tissue of chronic alcoholics. It is proposed that chronic alcohol abuse should be considered as an important factor in COVID-19-associated neurological complications.

Original language	English
Pages (from-to)	1024-1025
Number of pages	2
Journal	ACS Pharmacology and Translational Science
Volume	4
Issue number	2
Early online date	19 Mar 2021
DOIs	https://doi.org/10.1021/acsptsci.1c00073
Publication status	Published - 9 Apr 2021

Bibliographical note

Publisher Copyright:
© 2021 American Chemical Society.

Keywords

alcoholism
COVID-19
neurological manifestations
SARS-CoV-2

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1021/acsptsci.1c00073Licence: None: All rights reserved

Cite this

@article{380b117919fd42ebbbab85d2173552bc,

title = "COVID-19: Is There a Link between Alcohol Abuse and SARS-CoV-2-Induced Severe Neurological Manifestations?",

abstract = "For the first time, it is shown that severe COVID-19 associated genes (CCR2, DPP9, HSPA1L, TYK2, OAS1, ACE2, and TMPRSS2) were also upregulated in the brain tissue of chronic alcoholics. It is proposed that chronic alcohol abuse should be considered as an important factor in COVID-19-associated neurological complications.",

keywords = "alcoholism, COVID-19, neurological manifestations, SARS-CoV-2",

author = "Muhammad, {Jibran Sualeh} and Ruqaiyyah Siddiqui and Khan, {Naveed Ahmed}",

note = "Publisher Copyright: {\textcopyright} 2021 American Chemical Society.",

year = "2021",

month = apr,

day = "9",

doi = "10.1021/acsptsci.1c00073",

language = "English",

volume = "4",

pages = "1024--1025",

journal = "ACS Pharmacology and Translational Science",

issn = "2575-9108",

publisher = "American Chemical Society",

number = "2",

}

TY - JOUR

T1 - COVID-19

T2 - Is There a Link between Alcohol Abuse and SARS-CoV-2-Induced Severe Neurological Manifestations?

AU - Muhammad, Jibran Sualeh

AU - Siddiqui, Ruqaiyyah

AU - Khan, Naveed Ahmed

PY - 2021/4/9

Y1 - 2021/4/9

N2 - For the first time, it is shown that severe COVID-19 associated genes (CCR2, DPP9, HSPA1L, TYK2, OAS1, ACE2, and TMPRSS2) were also upregulated in the brain tissue of chronic alcoholics. It is proposed that chronic alcohol abuse should be considered as an important factor in COVID-19-associated neurological complications.

AB - For the first time, it is shown that severe COVID-19 associated genes (CCR2, DPP9, HSPA1L, TYK2, OAS1, ACE2, and TMPRSS2) were also upregulated in the brain tissue of chronic alcoholics. It is proposed that chronic alcohol abuse should be considered as an important factor in COVID-19-associated neurological complications.

KW - alcoholism

KW - COVID-19

KW - neurological manifestations

KW - SARS-CoV-2

UR - http://www.scopus.com/inward/record.url?scp=85103759090&partnerID=8YFLogxK

U2 - 10.1021/acsptsci.1c00073

DO - 10.1021/acsptsci.1c00073

M3 - Review article

AN - SCOPUS:85103759090

SN - 2575-9108

VL - 4

SP - 1024

EP - 1025

JO - ACS Pharmacology and Translational Science

JF - ACS Pharmacology and Translational Science

IS - 2

ER -

COVID-19: Is There a Link between Alcohol Abuse and SARS-CoV-2-Induced Severe Neurological Manifestations?

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Fingerprint

Cite this