Abstract
The authors report on a detailed insight into 112 patients with comorbidity of haematological conditions and coronavirus disease 2019 (COVID-19), admitted into nine National Health Services Trusts in the West Midlands Area of the United Kingdom, between 1st of March 2020 and 31st May 2020. In the study cohort, 82% of patients had a malignant haematological disorder whist 18% had a non-malignant haematological condition. Increasing age, breathlessness, reduction in oxygen saturation under 90% and abnormal chest x-ray were independently associated with higher mortality. Other long-term co-morbidities had no identified adverse impact in this population. Survival analysis demonstrated that the COVID-19 severity score had a significant adverse correlation on patient outcome. COVID-19 patients classified as low risk, based on their primary haematological condition, showed significantly shorter survival time than those in the high-risk category, which may be due to shielding strategy. The 55% overall mortality in this cohort suggests that patients with haematological conditions had higher mortality rate.
Original language | English |
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Pages (from-to) | e11-e14 |
Journal | British Journal of Haematology |
Volume | 192 |
Issue number | 1 |
Early online date | 5 Nov 2020 |
DOIs | |
Publication status | E-pub ahead of print - 5 Nov 2020 |
Bibliographical note
My contribution: Data Scientist, Research design and write-up of the analysis.Collaboration: Multidisciplinary Work with NHS, West Midlands Research Consortium.
About the Journal: The British Journal of Haematology is a peer-reviewed medical journal focusing on hematology and other blood-related topics. It's impact factor is 5.518 (2019, latest)
Keywords
- COVID-19
- COVID-19 Survival Analysis
- Coronavirus Pandemic
- Haematology patients
- Severity of COVID-19 Symptoms