Copper-catalyzed synthesis of purine-fused polycyclics

Gui-Rong Qu, Lei Liang, Hong-Ying Niu, Wei-Hao Rao, Hai-Ming Guo, John S Fossey

Research output: Contribution to journalArticlepeer-review

51 Citations (Scopus)

Abstract

A novel protocol for a Cu-catalyzed direct C((sp(2)))-H activation/intramolecular amination reaction of 6-anilinopurine nucleosides has been developed. This approach provides a new access to a variety of multiheterocyclic compounds from purine compounds via Cu-catalyzed intramolecular N-H bond tautomerism which are endowed with fluorescence.
Original languageEnglish
Pages (from-to)4494-7
Number of pages4
JournalOrganic Letters
Volume14
Issue number17
DOIs
Publication statusPublished - 2012

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