Continuous multi-step synthesis by extrusion – telescoping solvent-free reactions for greater efficiency

Deborah Crawford; Clodagh K. Miskimmin; John Cahir; S. L. James

doi:10.1039/c7cc06010f

Continuous multi-step synthesis by extrusion – telescoping solvent-free reactions for greater efficiency

Deborah Crawford, Clodagh K. Miskimmin, John Cahir, S. L. James

Research output: Contribution to journal › Article › peer-review

Abstract

Herein, we demonstrate that several reactions can be telescoped into a single continuous process and/or be carried out as a continuous multi-component reaction (MCR), by twin screw extrusion (TSE), in the complete absence of solvent.

Original language	English
Journal	Chemical Communications
DOIs	https://doi.org/10.1039/c7cc06010f
Publication status	Published - 2017

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10.1039/c7cc06010f

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title = "Continuous multi-step synthesis by extrusion – telescoping solvent-free reactions for greater efficiency",

abstract = "Herein, we demonstrate that several reactions can be telescoped into a single continuous process and/or be carried out as a continuous multi-component reaction (MCR), by twin screw extrusion (TSE), in the complete absence of solvent.",

author = "Deborah Crawford and Miskimmin, {Clodagh K.} and John Cahir and James, {S. L.}",

year = "2017",

doi = "10.1039/c7cc06010f",

language = "English",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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AU - Crawford, Deborah

AU - Miskimmin, Clodagh K.

AU - Cahir, John

AU - James, S. L.

PY - 2017

Y1 - 2017

N2 - Herein, we demonstrate that several reactions can be telescoped into a single continuous process and/or be carried out as a continuous multi-component reaction (MCR), by twin screw extrusion (TSE), in the complete absence of solvent.

AB - Herein, we demonstrate that several reactions can be telescoped into a single continuous process and/or be carried out as a continuous multi-component reaction (MCR), by twin screw extrusion (TSE), in the complete absence of solvent.

UR - http://dx.doi.org/10.1039/c7cc06010f

U2 - 10.1039/c7cc06010f

DO - 10.1039/c7cc06010f

M3 - Article

SN - 1359-7345

JO - Chemical Communications

JF - Chemical Communications

ER -

Continuous multi-step synthesis by extrusion – telescoping solvent-free reactions for greater efficiency

Abstract

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