Consumer safety considerations of skin and oral microbiome perturbation

Andrew J McBain, Iain Chapple

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)
215 Downloads (Pure)

Abstract

Microbiomes associated with human skin and the oral cavity are uniquely exposed to personal care regimes. Changes in the composition and activities of the microbial communities in these environments can be utilized to promote consumer health benefits, for example, by reducing the numbers, composition, or activities of microbes implicated in conditions such as acne, axillary odor, dandruff, and oral diseases. It is, however, important to ensure that innovative approaches for microbiome manipulation do not unsafely disrupt the microbiome or compromise health, and where major changes in the composition or activities of the microbiome may occur, these require evaluation to ensure that critical biological functions are unaffected. This article is based on a 2-day workshop held at SEAC Unilever, Sharnbrook, United Kingdom, involving 31 specialists in microbial risk assessment, skin and oral microbiome research, microbial ecology, bioinformatics, mathematical modeling, and immunology. The first day focused on understanding the potential implications of skin and oral microbiome perturbation, while approaches to characterize those perturbations were discussed during the second day. This article discusses the factors that the panel recommends be considered for personal care products that target the microbiomes of the skin and the oral cavity.
Original languageEnglish
Article numbere00051-19
JournalClinical Microbiology Reviews
Volume32
Issue number4
Early online date31 Jul 2019
DOIs
Publication statusPublished - Oct 2019

Bibliographical note

Copyright © 2019 American Society for Microbiology.

Keywords

  • Consumer safety
  • Hygiene
  • Oral microbiome
  • Personal care
  • Risk assessment
  • Skin microbiome

ASJC Scopus subject areas

  • Epidemiology
  • Immunology and Microbiology(all)
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Infectious Diseases

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