Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro

R Anderson; H C Steel; R Cockeran; A von Gottberg; L de Gouveia; K P Klugman; T J Mitchell; C Feldman

doi:10.1093/jac/dkm338

Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro

R Anderson
, H C Steel
, R Cockeran
, A von Gottberg
, L de Gouveia
, K P Klugman
, T J Mitchell
, C Feldman

Immunology and Immunotherapy

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

Abstract

To compare the effects of subinhibitory concentrations of amoxicillin, ceftriaxone, azithromycin, clarithromycin, erythromycin, telithromycin, clindamycin, ciprofloxacin, moxifloxacin, tobramycin and doxycycline on pneumolysin production by a macrolide-susceptible strain and two macrolide-resistant strains [erm(B) or mef(A)] of Streptococcus pneumoniae.

Original language	English
Pages (from-to)	1155-8
Number of pages	4
Journal	Journal of Antimicrobial Chemotherapy
Volume	60
Issue number	5
DOIs	https://doi.org/10.1093/jac/dkm338
Publication status	Published - Nov 2007

Keywords

Amoxicillin
Anti-Bacterial Agents
Bacterial Proteins
Ceftriaxone
Doxycycline
Drug Resistance, Multiple, Bacterial
Fluoroquinolones
Macrolides
Microbial Sensitivity Tests
Streptococcus pneumoniae
Streptolysins
Tobramycin

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10.1093/jac/dkm338

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Anderson, R., Steel, H. C., Cockeran, R., von Gottberg, A., de Gouveia, L., Klugman, K. P., Mitchell, T. J., & Feldman, C. (2007). Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro. Journal of Antimicrobial Chemotherapy, 60(5), 1155-8. https://doi.org/10.1093/jac/dkm338

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title = "Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro",

abstract = "To compare the effects of subinhibitory concentrations of amoxicillin, ceftriaxone, azithromycin, clarithromycin, erythromycin, telithromycin, clindamycin, ciprofloxacin, moxifloxacin, tobramycin and doxycycline on pneumolysin production by a macrolide-susceptible strain and two macrolide-resistant strains [erm(B) or mef(A)] of Streptococcus pneumoniae.",

keywords = "Amoxicillin, Anti-Bacterial Agents, Bacterial Proteins, Ceftriaxone, Doxycycline, Drug Resistance, Multiple, Bacterial, Fluoroquinolones, Macrolides, Microbial Sensitivity Tests, Streptococcus pneumoniae, Streptolysins, Tobramycin",

author = "R Anderson and Steel, \{H C\} and R Cockeran and \{von Gottberg\}, A and \{de Gouveia\}, L and Klugman, \{K P\} and Mitchell, \{T J\} and C Feldman",

year = "2007",

month = nov,

doi = "10.1093/jac/dkm338",

language = "English",

volume = "60",

pages = "1155--8",

journal = "Journal of Antimicrobial Chemotherapy",

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Anderson, R, Steel, HC, Cockeran, R, von Gottberg, A, de Gouveia, L, Klugman, KP, Mitchell, TJ & Feldman, C 2007, 'Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro', Journal of Antimicrobial Chemotherapy, vol. 60, no. 5, pp. 1155-8. https://doi.org/10.1093/jac/dkm338

Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro. / Anderson, R; Steel, H C; Cockeran, R et al.
In: Journal of Antimicrobial Chemotherapy, Vol. 60, No. 5, 11.2007, p. 1155-8.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro

AU - Anderson, R

AU - Steel, H C

AU - Cockeran, R

AU - von Gottberg, A

AU - de Gouveia, L

AU - Klugman, K P

AU - Mitchell, T J

AU - Feldman, C

PY - 2007/11

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N2 - To compare the effects of subinhibitory concentrations of amoxicillin, ceftriaxone, azithromycin, clarithromycin, erythromycin, telithromycin, clindamycin, ciprofloxacin, moxifloxacin, tobramycin and doxycycline on pneumolysin production by a macrolide-susceptible strain and two macrolide-resistant strains [erm(B) or mef(A)] of Streptococcus pneumoniae.

AB - To compare the effects of subinhibitory concentrations of amoxicillin, ceftriaxone, azithromycin, clarithromycin, erythromycin, telithromycin, clindamycin, ciprofloxacin, moxifloxacin, tobramycin and doxycycline on pneumolysin production by a macrolide-susceptible strain and two macrolide-resistant strains [erm(B) or mef(A)] of Streptococcus pneumoniae.

KW - Amoxicillin

KW - Anti-Bacterial Agents

KW - Bacterial Proteins

KW - Ceftriaxone

KW - Doxycycline

KW - Drug Resistance, Multiple, Bacterial

KW - Fluoroquinolones

KW - Macrolides

KW - Microbial Sensitivity Tests

KW - Streptococcus pneumoniae

KW - Streptolysins

KW - Tobramycin

U2 - 10.1093/jac/dkm338

DO - 10.1093/jac/dkm338

M3 - Article

C2 - 17848373

SN - 0305-7453

VL - 60

SP - 1155

EP - 1158

JO - Journal of Antimicrobial Chemotherapy

JF - Journal of Antimicrobial Chemotherapy

IS - 5

ER -

Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro

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Keywords

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