Combined Anti-Angiogenic Therapy Targeting PDGF and VEGF Receptors Lowers the Interstitial Fluid Pressure in a Murine Experimental Carcinoma

Agriculture & Biology

• vascular endothelial growth factor receptors 100%
• platelet-derived growth factor 78%
• extracellular fluids 71%
• carcinoma 61%
• therapeutics 45%
• neoplasms 44%
• mice 33%
• drug therapy 29%
• vascular endothelial growth factors 19%
• additive effect 14%
• blood vessels 11%
• paclitaxel 9%
• growth inhibitors 8%
• phosphotransferases (kinases) 6%
• drugs 4%
• uptake mechanisms 4%
• methodology 1%

Medicine & Life Sciences

• Vascular Endothelial Growth Factor Receptor 70%
• Platelet-Derived Growth Factor 67%
• Extracellular Fluid 66%
• Carcinoma 38%
• Pressure 37%
• Neoplasms 18%
• Drug Therapy 17%
• Vascular Endothelial Growth Factor A 12%
• Therapeutics 9%
• Growth Inhibitors 9%
• Vascular Remodeling 8%
• Imatinib Mesylate 8%
• Paclitaxel 7%
• Needles 6%
• Phosphotransferases 5%
• Blood Vessels 4%
• Pharmaceutical Preparations 3%

Chemistry

• Antiangiogenic 80%
• Interstitial 61%
• Pressure 33%
• Growth Factor 17%
• Additive 9%
• Drug 3%