Clinical significance of perfusion techniques utilising different physiological mechanisms to detect myocardial viability: A comparative study with myocardial contrast echocardiography and single photon emission computed tomography☆

M Hickman, R Janardhanan, Girish Dwivedi, L Burden, R Senior

Research output: Contribution to journalLetter

12 Citations (Scopus)

Abstract

Myocardial uptake using (99m)Tc-sestamibi single photon emission computed tomography (SPECT) depends largely on myocardial microvascular volume. Myocardial contrast echocardiography (MCE) is a relatively new technique that detects not only microvascular volume but also blood flow. These differing mechanisms may affect the relative accuracies of MCE and SPECT for detecting myocardial viability (MV) early after acute myocardial infarction (AMI) and thrombolysis. Accordingly 56 patients underwent resting transthoracic echocardiography, low-power MCE and SPECT 7+/-2 days following first AMI and thrombolysis. Contractile reserve (CR) was assessed 3 months following revascularization. The sensitivity and specificity of MCE and SPECT were 83% and 78% (p=ns) and 78% and 45% (p
Original languageEnglish
Pages (from-to)139-140
Number of pages2
JournalInternational Journal of Cardiology
Volume114
Issue number1
DOIs
Publication statusPublished - 2 Jan 2007

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