Abstract
OBJECTIVES: This study was designed to compare multidetector row computed tomography (MDCT) and CT-assisted hepatic arteriography (CTHA)/CT during arterial portography (CTAP)/angiography/contrast-enhanced CT (CECT) findings prospectively for accuracy in the detection of liver metastasis and vascular involvement of the tumor.
METHODS: The study included 43 patients with pancreatic cancer who were evaluated from September 2002 to December 2003. These patients underwent preoperative evaluation by angiography/CTHA/CTAP/CECT (7-mm thickness) and by MDCT (1.25-mm thickness).
RESULTS: The sensitivity, specificity, positive predictive value, and negative predictive value of liver metastasis diagnosis were all superior using MDCT relative to CTHA/CTAP. The diagnostic accuracy of liver metastasis for patients with tumors less than 10 mm in diameter was particularly superior with MDCT relative to CTHA/CTAP. The surgical and pathological findings of vascular involvement were more accurately diagnosed by MDCT than by CTHA/CTAP/angiography/CECT. Although MDCT findings were generally similar to surgical findings of vascular involvement, MDCT overestimated the incidence of pathological vascular involvement.
CONCLUSIONS: Multidetector row CT imaging can potentially offer more accurate staging of pancreatic cancer and may be useful to surgeons both in preoperative planning and for intraoperative guidance.
Original language | English |
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Pages (from-to) | 175-9 |
Number of pages | 5 |
Journal | Pancreas |
Volume | 34 |
Issue number | 2 |
DOIs | |
Publication status | Published - Mar 2007 |
Keywords
- Adult
- Aged
- Aged, 80 and over
- Angiography
- Biopsy
- Contrast Media
- Female
- Hepatic Artery
- Hepatic Veins
- Humans
- Liver Neoplasms
- Male
- Middle Aged
- Neoplasm Staging
- Pancreatic Neoplasms
- Portography
- Predictive Value of Tests
- Sensitivity and Specificity
- Tomography, X-Ray Computed