Clinical differences between bipolar and unipolar depression

Lisa Jones, Elizabeth Caesar

    Research output: Contribution to journalArticle

    98 Citations (Scopus)

    Abstract

    It is commonly - but wrongly - assumed that there are no important differences between the clinical presentations of major depressive disorder and bipolar depression. Here we compare clinical course variables and depressive symptom profiles in a large sample of individuals with major depressive disorder (n=593) and bipolar disorder (n=443). Clinical characteristics associated with a bipolar course included the presence of psychosis, diurnal mood variation and hypersomnia during depressive episodes, and a greater number of shorter depressive episodes. Such features should alert a clinician to a possible bipolar course. This is important because optimal management is not the same for bipolar and unipolar depression.
    Original languageEnglish
    Pages (from-to)388-389
    Number of pages2
    JournalBritish Journal of Psychiatry
    Volume192
    Issue number5
    DOIs
    Publication statusPublished - 1 May 2008

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