Clinical and biochemical manifestations of Cushing's

Georgia Ntali; Ashley Grossman; Niki Karavitaki

doi:10.1007/s11102-014-0631-4

Clinical and biochemical manifestations of Cushing's

Georgia Ntali, Ashley Grossman, Niki Karavitaki

Metabolism and Systems Science

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

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Abstract

INTRODUCTION: Cushing's syndrome is associated with a number of clinical manifestations and co-morbidities which may not resolve even after long-term remission leading to excessive mortality.

MATERIALS AND METHODS: This review summarizes the main manifestations of Cushing's syndrome (active or in remission) with particular focus on data from recently published literature.

CONCLUSION: Obesity and metabolic alterations, hypertension and cardio/cerebrovascular complications, hypercoagulability/thromboembolism, neuropsychiatric, muscle/skeletal and immune consequences remain the most challenging. Cardiovascular consequences and immunosuppression determine the main causes of death in Cushing's syndrome necessitating early intervention when possible.

Original language	English
Pages (from-to)	181-187
Number of pages	7
Journal	Pituitary
Volume	18
Issue number	2
Early online date	10 Jan 2015
DOIs	https://doi.org/10.1007/s11102-014-0631-4
Publication status	Published - Apr 2015

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Ntali_et_al_Clinical_and_biochemical_Pituitary_2015
Checked for eligibility: 31/03/2016. The final publication is available at Springer via http://dx.doi.org/10.1007/s11102-014-0631-4
Accepted author manuscript, 165 KBLicence: None: All rights reserved

Cite this

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AU - Grossman, Ashley

AU - Karavitaki, Niki

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AB - INTRODUCTION: Cushing's syndrome is associated with a number of clinical manifestations and co-morbidities which may not resolve even after long-term remission leading to excessive mortality.MATERIALS AND METHODS: This review summarizes the main manifestations of Cushing's syndrome (active or in remission) with particular focus on data from recently published literature.CONCLUSION: Obesity and metabolic alterations, hypertension and cardio/cerebrovascular complications, hypercoagulability/thromboembolism, neuropsychiatric, muscle/skeletal and immune consequences remain the most challenging. Cardiovascular consequences and immunosuppression determine the main causes of death in Cushing's syndrome necessitating early intervention when possible.

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Clinical and biochemical manifestations of Cushing's

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