Abstract
Fluoroquinolone-resistant avian Escherichia coli isolates from northern Georgia were investigated for gyrA and parC mutations. All isolates contained a mutation in GyrA replacing Ser83 with Leu; seven isolates also contained mutations replacing Asp87 with either Gly or Tyr. Random amplified polymorphic DNA analysis revealed that quinolone-resistant E. coli isolates were genetically diverse.
| Original language | English |
|---|---|
| Pages (from-to) | 2897-9 |
| Number of pages | 3 |
| Journal | Antimicrobial Agents and Chemotherapy |
| Volume | 44 |
| Issue number | 10 |
| Publication status | Published - Oct 2000 |
Keywords
- Animals
- Anti-Infective Agents
- DNA Gyrase
- DNA Topoisomerase IV
- DNA Topoisomerases, Type II
- DNA, Bacterial
- Escherichia coli
- Escherichia coli Infections
- Fluoroquinolones
- Georgia
- Nalidixic Acid
- Polymorphism, Restriction Fragment Length
- Poultry
- Poultry Diseases
- Reverse Transcriptase Polymerase Chain Reaction