Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease

M M Esiri, Z Nagy, M Z Smith, L Barnetson, A D Smith

Research output: Contribution to journalArticlepeer-review

404 Citations (Scopus)

Abstract

Cerebrovascular disease and Alzheimer's disease commonly occur together in the elderly and each may contribute to dementia. Here we present evidence that cerebrovascular disease significantly worsens cognitive performance in the earliest stages of Alzheimer's disease.

Original languageEnglish
Pages (from-to)919-20
Number of pages2
JournalThe Lancet
Volume354
Issue number9182
DOIs
Publication statusPublished - 11 Sep 1999

Keywords

  • Aged
  • Alzheimer Disease
  • Brain
  • Brain Mapping
  • Cerebrovascular Disorders
  • Cohort Studies
  • Dementia, Vascular
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Neuropsychological Tests
  • Risk Factors

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