TY - JOUR
T1 - Cellular memory and the histone code
AU - Turner, Bryan
PY - 2002/11/1
Y1 - 2002/11/1
N2 - The histone tails on the nucleosome surface are subject to enzyme-catalyzed modifications that may, singly or in combination, form a code specifying patterns of gene expression. Recent papers provide insights into how a combinatorial code might be set and read. They show how modification of one residue can influence that of another, even when they are located on different histones, and how modifications at specific genomic locations might be perpetuated on newly assembled chromatin.
AB - The histone tails on the nucleosome surface are subject to enzyme-catalyzed modifications that may, singly or in combination, form a code specifying patterns of gene expression. Recent papers provide insights into how a combinatorial code might be set and read. They show how modification of one residue can influence that of another, even when they are located on different histones, and how modifications at specific genomic locations might be perpetuated on newly assembled chromatin.
UR - http://www.scopus.com/inward/record.url?scp=0036850325&partnerID=8YFLogxK
U2 - 10.1016/S0092-8674(02)01080-2
DO - 10.1016/S0092-8674(02)01080-2
M3 - Article
C2 - 12419240
SN - 0092-8674
VL - 111
SP - 285
EP - 291
JO - Cell
JF - Cell
IS - 3
ER -