Cell adhesion: a new target for therapy

Christopher Buckley

Research output: Contribution to journalReview articlepeer-review

29 Citations (Scopus)


Intercellular adhesive events are involved in a wide range of biological processes, including pattern formation and morphogenesis during development, immune responses, leukocyte recirculation, wound repair, tumour growth and metastasis. In the multicellular state, signals from cell adhesion molecules, along with those from growth factor and cytokine receptors, provide a range of information to the cell that is integrated to yield a final message, perhaps to maintain the cell cycle (if it is a stem cell) or follow a path towards terminal differentiation. Aberrant cell adhesion plays a key role in many developmental defects, acute and chronic inflammatory disease and cancer.
Original languageEnglish
Pages (from-to)449-456
Number of pages8
JournalMolecular Medicine
Publication statusPublished - Oct 1997


Dive into the research topics of 'Cell adhesion: a new target for therapy'. Together they form a unique fingerprint.

Cite this