Can combining different risk interventions into a single formulation contribute to improved cardiovascular disease risk reduction? Rationale and design for an international, open-label program to assess the effectiveness of a single pill (amlodipine/atorvastatin) to attain recommended target levels for blood pressure and lipids (The JEWEL Program)

Frederick Hobbs, G Gensini, GBJ Mancini, AJ Manolis, B Bauer, S Bohler, J Genest, R Feldman, P Harvey, TG Jenssen, M Metcalfe, M Marques da Silva

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    Medicine and Dentistry

    Biochemistry, Genetics and Molecular Biology

    Pharmacology, Toxicology and Pharmaceutical Science