Boronate ester cross-linked PVA hydrogels for the capture and H2O2-mediated release of active fluorophores

George T. Williams, Adam C. Sedgwick, Sajal Sen, Lauren Gwynne, Jordan E. Gardiner, James T. Brewster, Jennifer R. Hiscock, Tony D. James, A. Toby A. Jenkins, Jonathan L. Sessler

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


A new set of PVA hydrogels were formed using the boronate ester fluorescent probe PF1 and the novel boronate fluorescent probe PT1 as the covalent crosslinkers. Treatment with aqueous H 2O 2 allowed triggered release of the fluorescent dye accompanied by complete dissolution of the hydrogel.

Original languageEnglish
Pages (from-to)5516-5519
Number of pages4
JournalChemical Communications
Issue number41
Publication statusPublished - 7 Apr 2020

Bibliographical note

Funding Information:
The authors would like to thank the EPSRC for grant EP/ R003556/1. G. T. W. would like to thank the EPSRC and Public Health England. G. T. W. and J. R. H. would like to thank the global challenges doctoral centre at the University of Kent for funding. A. C. S. and A. T. A. J. wish to thank the EPSRC for funding on smart-wound plasma – EP/R003939/1. This work was supported in part by grant MR/N0137941/1 for the GW4 BIOMED DTP, awarded to the Universities of Bath, Bristol, Cardiff and Exeter from the Medical Research Council (MRC)/ UKRI. T. D. J. wishes to thank the Royal Society for a Wolfson Research Merit Award. The work in Austin was supported by the National Institutes of Health (R01 GM103790 to J. L. S.) and the Robert A. Welch Foundation (F-0018 to J. L. S.). A. C. S. would also like to acknowledge use of a Bruker AVIII HD 500 with Prodigy liquid nitrogen cryoprobe supported by NIH grant 1 S10 OD021508. All data supporting this study are provided as ESI† accompanying this paper.

Publisher Copyright:
© 2020 The Royal Society of Chemistry.

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


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