Blood cadmium may be associated with bladder carcinogenesis: The Belgian case–control study on bladder cancer

E Kellen, Maurice Zeegers, E Hond, F Buntinx

    Research output: Contribution to journalArticle

    79 Citations (Scopus)

    Abstract

    BACKGROUND: The aim of this study was to assess the relationship between exposure to cadmium and bladder cancer risk. METHODS: We conducted a case-control study in Belgium and measured the blood levels of cadmium in 172 bladder cases and 359 population controls. The data were analyzed as tertiles after logarithmic transformation. Cut-off points were based on the levels among the controls. Logistic regression was performed to calculate odds ratios (ORs) for bladder cancer occurrence with corresponding 95% confidence intervals (95% CI). RESULTS: After adjustment for sex, age, and occupational exposure to PAHs or aromatic amines, the OR for cadmium was 8.3 (95% CI 5.0-13.8) comparing the highest to the lowest tertile (p for trend
    Original languageEnglish
    Pages (from-to)77-82
    Number of pages6
    JournalCancer Detection and Prevention
    Volume31
    Issue number1
    DOIs
    Publication statusPublished - 1 Jan 2007

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