Bioreductive molecular probe: fluorescence signalling upon reduction of an azo group

Manikandan Kadirvel; Nicholas J.W. Rattray; Ramkumar Rajendran; Waleed A. Zalloum; Abdul Gbaj; Constantinos Demonacos; Elena V. Bichenkova; Sally Freeman

doi:10.1039/c0nj00849d

Bioreductive molecular probe: fluorescence signalling upon reduction of an azo group

Manikandan Kadirvel
, Nicholas J.W. Rattray
, Ramkumar Rajendran
, Waleed A. Zalloum
, Abdul Gbaj
, Constantinos Demonacos
, Elena V. Bichenkova
, Sally Freeman

Chemical Engineering

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

The intramolecular heterodimer probe 4-O-dabsyl-2-O-dansyl-myo-inositol-1, 3,5-orthoformate undergoes biomimetic reduction of the azo bond in the dabsyl group to give a fluorescence emission band at 560 nm. This is attributed to the loss of energy transfer between the fluorophore (dansyl) and quencher (dabsyl) groups as a result of the formation of 4-O-(4-aminobenzene sulfonyl)-2-O-dansyl- myo-inositol-1,3,5-orthoformate.

Original language	English
Pages (from-to)	701-708
Number of pages	8
Journal	New Journal of Chemistry
Volume	35
Issue number	3
Early online date	4 Jan 2011
DOIs	https://doi.org/10.1039/c0nj00849d
Publication status	Published - 1 Mar 2011

ASJC Scopus subject areas

Catalysis
General Chemistry
Materials Chemistry

Access to Document

10.1039/c0nj00849d

Cite this

@article{66fb85bf827d4b5d952188e1f088df6d,

title = "Bioreductive molecular probe: fluorescence signalling upon reduction of an azo group",

abstract = "The intramolecular heterodimer probe 4-O-dabsyl-2-O-dansyl-myo-inositol-1, 3,5-orthoformate undergoes biomimetic reduction of the azo bond in the dabsyl group to give a fluorescence emission band at 560 nm. This is attributed to the loss of energy transfer between the fluorophore (dansyl) and quencher (dabsyl) groups as a result of the formation of 4-O-(4-aminobenzene sulfonyl)-2-O-dansyl- myo-inositol-1,3,5-orthoformate.",

author = "Manikandan Kadirvel and Rattray, \{Nicholas J.W.\} and Ramkumar Rajendran and Zalloum, \{Waleed A.\} and Abdul Gbaj and Constantinos Demonacos and Bichenkova, \{Elena V.\} and Sally Freeman",

year = "2011",

month = mar,

day = "1",

doi = "10.1039/c0nj00849d",

language = "English",

volume = "35",

pages = "701--708",

journal = "New Journal of Chemistry",

issn = "1144-0546",

publisher = "Royal Society of Chemistry",

number = "3",

}

TY - JOUR

T1 - Bioreductive molecular probe

T2 - fluorescence signalling upon reduction of an azo group

AU - Kadirvel, Manikandan

AU - Rattray, Nicholas J.W.

AU - Rajendran, Ramkumar

AU - Zalloum, Waleed A.

AU - Gbaj, Abdul

AU - Demonacos, Constantinos

AU - Bichenkova, Elena V.

AU - Freeman, Sally

PY - 2011/3/1

Y1 - 2011/3/1

N2 - The intramolecular heterodimer probe 4-O-dabsyl-2-O-dansyl-myo-inositol-1, 3,5-orthoformate undergoes biomimetic reduction of the azo bond in the dabsyl group to give a fluorescence emission band at 560 nm. This is attributed to the loss of energy transfer between the fluorophore (dansyl) and quencher (dabsyl) groups as a result of the formation of 4-O-(4-aminobenzene sulfonyl)-2-O-dansyl- myo-inositol-1,3,5-orthoformate.

AB - The intramolecular heterodimer probe 4-O-dabsyl-2-O-dansyl-myo-inositol-1, 3,5-orthoformate undergoes biomimetic reduction of the azo bond in the dabsyl group to give a fluorescence emission band at 560 nm. This is attributed to the loss of energy transfer between the fluorophore (dansyl) and quencher (dabsyl) groups as a result of the formation of 4-O-(4-aminobenzene sulfonyl)-2-O-dansyl- myo-inositol-1,3,5-orthoformate.

UR - https://www.scopus.com/pages/publications/79952207867

U2 - 10.1039/c0nj00849d

DO - 10.1039/c0nj00849d

M3 - Article

AN - SCOPUS:79952207867

SN - 1144-0546

VL - 35

SP - 701

EP - 708

JO - New Journal of Chemistry

JF - New Journal of Chemistry

IS - 3

ER -

Bioreductive molecular probe: fluorescence signalling upon reduction of an azo group

Abstract

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this